Publication result detail
Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles
MRAVEC, F.; CHIU, C.; CHANG, C.
Original Title
Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles
English Title
Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles
Type
Chapter in a book
Original Abstract
Ion pair amphiphile, prepared from mixed cationic/anionic surfactants, has a pseudodouble-chain structure and can be used as a raw material to form a vesicular structure, or catanionic vesicle, in aqueous phase. It has been demonstrated that catanionic vesicles could be fabricated from the ion pair amphiphile hexadecyltrimethylammonium-dodecylsulfate (HTMA:DS) by using a forced formation process with the addition of double-chain cationic surfactants, dialkyldimethylammonium bromide (DXDAB), and the physical stability of the HTMA:DS/DXDAB catanionic vesicles could be further improved in the presence of cholesterol. Through the analysis of bilayer fluidity and solvation, as well as the data integration of different analysis methods, combined with molecular dynamics simulations, the complex effects of the added cholesterol on the molecular arrangement and interaction in the bilayer structures of the HTMA:DS/DXDAB catanionic vesicles were elucidated.
English abstract
Ion pair amphiphile, prepared from mixed cationic/anionic surfactants, has a pseudodouble-chain structure and can be used as a raw material to form a vesicular structure, or catanionic vesicle, in aqueous phase. It has been demonstrated that catanionic vesicles could be fabricated from the ion pair amphiphile hexadecyltrimethylammonium-dodecylsulfate (HTMA:DS) by using a forced formation process with the addition of double-chain cationic surfactants, dialkyldimethylammonium bromide (DXDAB), and the physical stability of the HTMA:DS/DXDAB catanionic vesicles could be further improved in the presence of cholesterol. Through the analysis of bilayer fluidity and solvation, as well as the data integration of different analysis methods, combined with molecular dynamics simulations, the complex effects of the added cholesterol on the molecular arrangement and interaction in the bilayer structures of the HTMA:DS/DXDAB catanionic vesicles were elucidated.
Keywords
Bilayer fluidity; Catanionic bilayer; Catanionic vesicle; Ion pair amphiphile; Vesicular structure
Key words in English
Bilayer fluidity; Catanionic bilayer; Catanionic vesicle; Ion pair amphiphile; Vesicular structure
Authors
MRAVEC, F.; CHIU, C.; CHANG, C.
RIV year
2026
Released
07.10.2025
Publisher
Springer Nature Singapore
Location
Singapore
ISBN
9789819667277
Book
Physical Chemistry in Action, Colloids and Interfacial Dynamics
Pages from
247
Pages to
266
Pages count
20
BibTex
@inbook{BUT199015,
author="{} and Filip {Mravec} and {} and {} and {} and Chien-Hsiang {Chang} and {} and {} and {}",
title="Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles",
booktitle="Physical Chemistry in Action, Colloids and Interfacial Dynamics",
year="2025",
publisher="Springer Nature Singapore",
address="Singapore",
pages="247--266",
isbn="9789819667277"
}