Publication detail

Optimization of analytical methods for the determination of residues of selected pharmaceuticals in the aquatic enviroment.

JÁROVÁ, K. VÁVROVÁ, M. OBORNÁ, J.

Original Title

Optimization of analytical methods for the determination of residues of selected pharmaceuticals in the aquatic enviroment.

Type

conference proceedings

Language

English

Original Abstract

The present study deals with the determination of residues of selected antibiotics from the group of sulfonamides in water ecosystem. The target analytes included ten sulfonamides: sulfaguanidine, sulfadiazine, sulfathiazole, sulfapyridine, sulfamerazine, sulfadimidine, sulfamethoxazole, sulfadoxine, sulfaclozine and sulfadimethoxine. The optimized methods should be applied for the matrices as surface or waste water and bottom river sediment. The attention was first focused on optimization of the method for identification and quantification of selected sulfonamides using high-performance liquid chromatography coupled with diode array detector (HPLC/DAD). The methods of solid phase extraction (SPE) and pressurized solvent extraction (PSE) were optimized for extraction, pre-concentration and purification of the matrices.

Keywords

sulfonamides, high - performance liquid chromatography, solid phase extraction, pressured solvent extraction

Authors

JÁROVÁ, K.; VÁVROVÁ, M.; OBORNÁ, J.

Released

20. 10. 2014

Location

Brno, Czech Republic

ISBN

978-80-904959-2-0

Book

11th International Interdisciplinary Meeting on Bioanalysis

Pages from

262

Pages to

265

Pages count

4

URL

http:/www.ce-ce.org/CECE2014/CECEproceedings_full.pdf

BibTex

@proceedings{BUT112461,
  editor="Kateřina {Járová} and Milada {Vávrová} and Jana {Oborná}",
  title="Optimization of analytical methods for the determination of residues of selected pharmaceuticals in the aquatic enviroment.",
  year="2014",
  pages="262--265",
  address="Brno, Czech Republic",
  isbn="978-80-904959-2-0",
  url="http:/www.ce-ce.org/CECE2014/CECEproceedings_full.pdf"
}