Publication detail

Identification of acetaldehyde based on plasmonic patterns of a gold nanostructure conjugated with chromophore and H2O2: a new platform for the rapid and low-cost analysis of carcinogenic agents by colorimetric affordable test strip (CATS)

Farshchi, F. Saadati, A. Bahavarnia, F. Hasanzadeh, M. Shadjou, N.

Original Title

Identification of acetaldehyde based on plasmonic patterns of a gold nanostructure conjugated with chromophore and H2O2: a new platform for the rapid and low-cost analysis of carcinogenic agents by colorimetric affordable test strip (CATS)

Type

journal article in Web of Science

Language

English

Original Abstract

Acetaldehyde, a prevalent carbonyl compound in fermented foods, poses challenges in various applications due to its reactivity. This study addresses the need for efficient acetaldehyde detection methods across biotechnological, environmental, pharmaceutical, and food sectors. Herein, we present a novel colorimetric/UV spectrophotometric approach utilizing gold nanoparticles (AuNPs), particularly gold nano-flowers (AuNFs), for sensitive acetaldehyde identification. The method exhibits a notable sensitivity, detecting acetaldehyde at concentrations as low as 0.1 mu M. The mechanism involves the interaction of acetaldehyde molecules with AuNFs, leading to a significant change in the absorbance spectrum, which serves as the basis for detection. Moreover, its applicability extends to human biofluids, notably urine samples. Integration with a cost-effective one-drop microfluidic colorimetric device (OD-mu PCD) enables the development of an affordable test strip (CATS). This semi-analytical device, employing a multichannel OD-mu PCD, facilitates real-time analysis of acetaldehyde in human samples. Our findings demonstrate the pioneering utilization of AuNPs for selective and sensitive acetaldehyde detection, promising advancements in environmental and occupational safety standards, and laying a foundation for enhanced detection and monitoring of related volatile organic compounds (VOCs).

Keywords

analytical devices; optical-properties; nanoparticles; aldehydes; samples; sensorsize

Authors

Farshchi, F.; Saadati, A.; Bahavarnia, F.; Hasanzadeh, M.; Shadjou, N.

Released

10. 5. 2024

Publisher

ROYAL SOC CHEMISTRY

Location

CAMBRIDGE

ISBN

1525-7797

Periodical

BIOMACROMOLECULES

Year of study

14

Number

22

State

United States of America

Pages from

15755

Pages to

15765

Pages count

11

URL

https://pubs.rsc.org/en/content/articlelanding/2024/ra/d4ra02814g

Full text in the Digital Library

http://hdl.handle.net/11012/249531

BibTex

@article{BUT188814,
  author="Fatemeh {Farshchi} and Arezoo {Saadati} and Farnaz {Bahavarnia} and Mohammad {Hasanzadeh} and Nasrin {Shadjou}",
  title="Identification of acetaldehyde based on plasmonic patterns of a gold nanostructure conjugated with chromophore and H2O2: a new platform for the rapid and low-cost analysis of carcinogenic agents by colorimetric affordable test strip (CATS)",
  journal="BIOMACROMOLECULES",
  year="2024",
  volume="14",
  number="22",
  pages="15755--15765",
  doi="10.1039/d4ra02814g",
  issn="1525-7797",
  url="https://pubs.rsc.org/en/content/articlelanding/2024/ra/d4ra02814g"
}