Publication detail

Pregnancy induces retinal microvascular changes indicating cardio-metabolic stress

DATHAN-STUMPF, A. STEPAN, H. ORSÁGOVÁ, E. JAKUBÍČEK, R. BERBÉE, C. SEIDENSPINNER, M. KOLÁŘ, R. RAUSCHER, F.

Original Title

Type

journal article in Web of Science

Language

English

Original Abstract

We performed longitudinal examinations of the arterial retinal microvasculature using Adaptive Optics Retinal Imaging in a 30-year-old healthy woman with twin pregnancy from the 23rd week of gestation (wog) to three days postpartum. Two blinded graders recorded the average wall-to-lumen ratio (WLR) of the examined retinal artery. There was a significant increase in the mean WLR over the course of pregnancy followed by a decreasing WLR from the 37th wog. The demonstrated changes in WLR may be an expression of vascular remodeling and adaptation to volume load which indicates that pregnancy can be viewed as a cardiovascular stress test.

Keywords

retina; vascularity; adaptive optics; pregnancy

Authors

DATHAN-STUMPF, A.; STEPAN, H.; ORSÁGOVÁ, E.; JAKUBÍČEK, R.; BERBÉE, C.; SEIDENSPINNER, M.; KOLÁŘ, R.; RAUSCHER, F.

Released

4. 3. 2024

Publisher

ELSEVIER SCI LTD

Location

London

ISBN

2210-7789

Periodical

Pregnancy Hypertension

Year of study

Number

March 2024

State

Kingdom of the Netherlands

Pages from

Pages to

Pages count

URL

https://www.sciencedirect.com/science/article/pii/S2210778923003884

BibTex

@article{BUT189776,
  author="Anne {Dathan-Stumpf} and Holger {Stepan} and Eva {Orságová} and Roman {Jakubíček} and Clara {Berbée} and Marie-Louise {Seidenspinner} and Radim {Kolář} and Franziska G. {Rauscher}",
  title="Pregnancy induces retinal microvascular changes indicating cardio-metabolic stress",
  journal="Pregnancy Hypertension",
  year="2024",
  volume="35",
  number="March 2024",
  pages="30--31",
  doi="10.1016/j.preghy.2023.12.004",
  issn="2210-7789",
  url="https://www.sciencedirect.com/science/article/pii/S2210778923003884"
}