Publication detail

Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion

PLEŠINGER, F. SMÍŠEK, R. JURÁK, P. KOŠČOVÁ, Z. VARGOVÁ, E.

Original Title

Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion

Type

journal article in Web of Science

Language

English

Original Abstract

Electrical cardioversion presents one of the treatment options for atrial fibrillation (AF). However, the early recurrence rate is high, reaching similar to 40% three months after the procedure. Features based on vectorcardiographic signals were explored to find association with early recurrence of AF. Eighty-four patients with non-paroxysmal AF referred to electrical cardioversion were prospectively studied; early AF recurrence was present in 40 (47.6%). Patients underwent 24-h Holter ECG monitoring three months after the procedure to assess AF recurrence. Pre-procedural 12-lead ECGs (10 s, 1 kHz) were recorded and automatically analyzed. We explored associations of VCG-based features with early AF recurrence. Two features were strongly associated with AF recurrence: (1) a mean VCG (y-axis) signal slope in a window starting 145 ms before QRS center, lasting for 190 ms (AUC 0.778, p < 0.001), and (2) a mean VCG (z-axis) signal slope in a window starting 60 ms after QRS center, lasting for 465 ms (AUC 0.744, p < 0.001). These features showed higher association to the outcome than eighteen baseline clinical features. Our approach revealed features based on a slope of vectorcardiographic signals. This work also suggests that state of ventricles strongly affects the AF recurrence after electrical cardioversion.

Keywords

ECG; VCG; Cardioversion; Signal processing; Atrial fibrillation

Authors

PLEŠINGER, F.; SMÍŠEK, R.; JURÁK, P.; KOŠČOVÁ, Z.; VARGOVÁ, E.

Released

8. 1. 2025

Publisher

NATURE PORTFOLIO

Location

BERLIN

ISBN

2045-2322

Periodical

Scientific Reports

Year of study

15

Number

1257

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1

Pages to

10

Pages count

10

URL

BibTex

@article{BUT197305,
  author="PLEŠINGER, F. and SMÍŠEK, R. and JURÁK, P. and KOŠČOVÁ, Z. and VARGOVÁ, E.",
  title="Automatically optimized vectorcardiographic features are associated with recurrence of atrial fibrillation after electrical cardioversion",
  journal="Scientific Reports",
  year="2025",
  volume="15",
  number="1257",
  pages="1--10",
  doi="10.1038/s41598-025-85340-4",
  issn="2045-2322",
  url="https://www.nature.com/articles/s41598-025-85340-4"
}