Publication detail
A low-cost picowatt calorimeter using a flexible printed circuit board
ZHU, H. ZHANG, Y. WANG, L. BRODSKÝ, J. GABLECH, I. FENG, J. YAN, Q.L. YANG, S. LEE, L. NEUŽIL, P.
Original Title
A low-cost picowatt calorimeter using a flexible printed circuit board
Type
journal article in Web of Science
Language
English
Original Abstract
Calorimetry is crucial in biology, chemistry, physics, and pharmaceutical research, enabling the detection of heat changes at nanowatt and picowatt levels. However, traditional calorimetry systems are often limited by high costs and complex fabrication processes. Here, we reduce the cost and fabrication complexity of microcalorimeters by utilizing widely available flexible printed circuit manufacturing processes. This device achieves temperature and power resolutions of ≈ 6 μK and ≈ 654 pW in vacuum. Its feasibility is validated across a wide range of measurements, including salt crystallization, protein crystallization, and cellular metabolism. Our concept enhances the accessibility of microcalorimeters for high-resolution thermal analysis, which is challenging for conventional calorimeters.
Keywords
calorimetry; thermal analysis; flexible printed circuit board
Authors
ZHU, H.; ZHANG, Y.; WANG, L.; BRODSKÝ, J.; GABLECH, I.; FENG, J.; YAN, Q.L.; YANG, S.; LEE, L.; NEUŽIL, P.
Released
27. 3. 2025
Publisher
Nature Portfolio
Location
ENGLAND
ISBN
2041-1723
Periodical
NATURE COMMUNICATIONS
Year of study
16
Number
March
State
United Kingdom of Great Britain and Northern Ireland
Pages from
1
Pages to
13
Pages count
13
URL
Full text in the Digital Library
BibTex
@article{BUT197504,
author="Hanliang {Zhu} and Yue {Zhang} and Lan {Wang} and Jan {Brodský} and Imrich {Gablech} and Jianguo {Feng} and Qi-Long {Yan} and Shujie {Yang} and Luke P. {Lee} and Pavel {Neužil}",
title="A low-cost picowatt calorimeter using a flexible printed circuit board",
journal="NATURE COMMUNICATIONS",
year="2025",
volume="16",
number="March",
pages="13",
doi="10.1038/s41467-025-58025-9",
issn="2041-1723",
url="https://www.nature.com/articles/s41467-025-58025-9"
}