Publication detail

A low-cost picowatt calorimeter using a flexible printed circuit board

ZHU, H. ZHANG, Y. WANG, L. BRODSKÝ, J. GABLECH, I. FENG, J. YAN, Q.L. YANG, S. LEE, L. NEUŽIL, P.

Original Title

A low-cost picowatt calorimeter using a flexible printed circuit board

Type

journal article in Web of Science

Language

English

Original Abstract

Calorimetry is crucial in biology, chemistry, physics, and pharmaceutical research, enabling the detection of heat changes at nanowatt and picowatt levels. However, traditional calorimetry systems are often limited by high costs and complex fabrication processes. Here, we reduce the cost and fabrication complexity of microcalorimeters by utilizing widely available flexible printed circuit manufacturing processes. This device achieves temperature and power resolutions of ≈ 6 μK and ≈ 654 pW in vacuum. Its feasibility is validated across a wide range of measurements, including salt crystallization, protein crystallization, and cellular metabolism. Our concept enhances the accessibility of microcalorimeters for high-resolution thermal analysis, which is challenging for conventional calorimeters.

Keywords

calorimetry; thermal analysis; flexible printed circuit board

Authors

ZHU, H.; ZHANG, Y.; WANG, L.; BRODSKÝ, J.; GABLECH, I.; FENG, J.; YAN, Q.L.; YANG, S.; LEE, L.; NEUŽIL, P.

Released

27. 3. 2025

Publisher

Nature Portfolio

Location

ENGLAND

ISBN

2041-1723

Periodical

NATURE COMMUNICATIONS

Year of study

16

Number

March

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1

Pages to

13

Pages count

13

URL

https://www.nature.com/articles/s41467-025-58025-9

Full text in the Digital Library

http://hdl.handle.net/11012/251185

BibTex

@article{BUT197504,
  author="Hanliang {Zhu} and Yue {Zhang} and Lan {Wang} and Jan {Brodský} and Imrich {Gablech} and Jianguo {Feng} and Qi-Long {Yan} and Shujie {Yang} and Luke P. {Lee} and Pavel {Neužil}",
  title="A low-cost picowatt calorimeter using a flexible printed circuit board",
  journal="NATURE COMMUNICATIONS",
  year="2025",
  volume="16",
  number="March",
  pages="13",
  doi="10.1038/s41467-025-58025-9",
  issn="2041-1723",
  url="https://www.nature.com/articles/s41467-025-58025-9"
}