Publication detail

No hyponatremia despite continuous plasma sodium decline in female runners during a seven stage ultramarathon

CHLÍBKOVÁ, D. FILIPENSKÁ, M. KNECHTLE, B. RAUTER, S. TRNKA, M. WEISS, K. ROSEMANN, T.

Original Title

No hyponatremia despite continuous plasma sodium decline in female runners during a seven stage ultramarathon

Type

journal article in Web of Science

Language

English

Original Abstract

The role of sodium supplements and sex in the occurrence of exercise-associated hyponatremia (EAH) remains controversial. This study investigated hydration status in ultrarunners (19 males and 9 females) who completed seven marathons over seven consecutive days. Due to the limited number of female participants, no statistical comparison between sexes was performed. Plasma sodium concentration ([Na+]) and multiple hydration markers were assessed before, during, and after the race. Reported sodium supplement consumption showed no association with plasma [Na+]. An overall decline in plasma [Na+] was observed in females (regression slope = -1.278, p = 0.02) across the event, whereas no significant change was detected in males (slope = -0.325, p = 0.57). Additionally, no significant associations were found between plasma [Na+] and other monitored variables, including sodium supplement intake, pre-race hydration strategy, body mass, total body water, plasma osmolality, hematocrit, hemoglobin, urine specific gravity, urinary [Na+], thirst rating, or fluid intake reported pre-, during, and post-stage. No cases of symptomatic or asymptomatic hyponatremia were identified, suggesting that total fluid and sodium intake were adequate to maintain fluid-electrolyte balance and prevent EAH in both sexes.

Keywords

exercise-associated hyponatremia, plasma sodium, female sex

Authors

CHLÍBKOVÁ, D.; FILIPENSKÁ, M.; KNECHTLE, B.; RAUTER, S.; TRNKA, M.; WEISS, K.; ROSEMANN, T.

Released

3. 4. 2025

Publisher

Nature Portfolio

Location

Spojené království Velké Británie a Severního Irska

ISBN

2045-2322

Periodical

Scientific Reports

Year of study

15

Number

1

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1

Pages to

15

Pages count

15

URL

https://www.nature.com/articles/s41598-025-90987-0

Full text in the Digital Library

http://hdl.handle.net/11012/251058

BibTex

@article{BUT197618,
  author="Daniela {Chlíbková} and Marina {Filipenská} and Beat {Knechtle} and Samo {Rauter} and Martin {Trnka} and Katja {Weiss} and Thomas {Rosemann}",
  title="No hyponatremia despite continuous plasma sodium decline in female runners during a seven stage ultramarathon",
  journal="Scientific Reports",
  year="2025",
  volume="15",
  number="1",
  pages="1--15",
  doi="10.1038/s41598-025-90987-0",
  issn="2045-2322",
  url="https://www.nature.com/articles/s41598-025-90987-0"
}