Publication detail

Techno-economic assessment of polyhydroxyalkanoates production from lignocellulosic biomass employing halophilic and thermophilic microbial platform: Effect of fermentation conditions and downstream operations

OZTURK, A. KOUŘILOVÁ, X. BUCHTÍKOVÁ, I. OBRUČA, S.

Original Title

Techno-economic assessment of polyhydroxyalkanoates production from lignocellulosic biomass employing halophilic and thermophilic microbial platform: Effect of fermentation conditions and downstream operations

Type

journal article in Web of Science

Language

English

Original Abstract

This study investigates the techno-economic viability of synthesizing polyhydroxyalkanoates (PHA) from lignocellulosic biomass through the utilization of extremophilic microorganisms, framed within the context of Next-Generation Industrial Biotechnology (NGIB). Microbial platforms characterized by halophilic and thermophilic properties, specifically Halomonas halophila and Caldimonas thermodepolymerans, were utilized to tackle issues related to sterility demands, process efficiency, and sustainability. Scenarios incorporating rice straw and discarded softwood, which are low-cost feedstocks that do not interfere with the human food supply, were modeled as resources for PHA biosynthesis. Additionally, a comparison was conducted between traditional chloroform extraction methods and environmentally friendly hypotonic lysis for the recovery of PHA from extremophilic microbial cultures prone to this treatment. Economic indicators such as net present value, internal rate of return, and payback period, were analyzed to evaluate the economic viability of the process. Findings indicate that the incorporation of extremophilic microorganisms alongside waste valorization techniques could make PHA production economically viable, thereby decreasing dependence on fossil-derived plastics while simultaneously addressing ecological issues. This initial study highlights the necessity for subsequent scale-up investigations to authenticate the proposed methodology, which shows potential for the sustainable production of PHA.

Keywords

Polyhydroxyalkanoates; Process simulation; Techno-economic assessment; Halomonas halophila; Caldimonas thermodepolymerans

Authors

OZTURK, A.; KOUŘILOVÁ, X.; BUCHTÍKOVÁ, I.; OBRUČA, S.

Released

15. 7. 2025

Publisher

PERGAMON-ELSEVIER SCIENCE LTD

Location

OXFORD

ISBN

1879-2456

Periodical

WASTE MANAGEMENT

Year of study

203

Number

7

State

United States of America

Pages count

13

URL

https://www.sciencedirect.com/science/article/pii/S0956053X25002983?via%3Dihub

BibTex

@article{BUT198107,
  author="Abdullah Bilal {Ozturk} and Xenie {Kouřilová} and Iva {Buchtíková} and Stanislav {Obruča}",
  title="Techno-economic assessment of polyhydroxyalkanoates production from lignocellulosic biomass employing halophilic and thermophilic microbial platform: Effect of fermentation conditions and downstream operations",
  journal="WASTE MANAGEMENT",
  year="2025",
  volume="203",
  number="7",
  pages="13",
  doi="10.1016/j.wasman.2025.114887",
  issn="1879-2456",
  url="https://www.sciencedirect.com/science/article/pii/S0956053X25002983?via%3Dihub"
}