Publication detail

The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

REJMONTOVÁ, P., KOVALČÍK, A., HUMPOLÍČEK, P., CAPÁKOVÁ, Z., WRZECIONKO, E., SÁHA, P.

Original Title

The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds

Type

journal article in Web of Science

Language

English

Original Abstract

The mechanical properties of poly(vinyl alcohol) (PVA)-based scaffolds were successfully improved. The improvements in mechanical properties correlated with the amount of Kraft lignin in PVA matrices. The critical property for any scaffold is its capacity to allow cells to ingrow and survive within its internal structure. The ingrowth of cells was tested using bioreactors creating simulated in vivo conditions. In the context of all the mentioned parameters, the most advantageous properties were exhibited by the scaffold containing 99 wt% PVA and 1 wt% Kraft lignin. The composites with 1 wt% Kraft lignin exhibited sufficient mechanical stability, a lack of cytotoxicity, and mainly the ability to allow the ingrowth of cells into the scaffold in a rotation bioreactor.

Keywords

cytotoxicity; lignin; mechanical properties; poly(vinyl alcohol); scaffolds,

Authors

REJMONTOVÁ, P., KOVALČÍK, A., HUMPOLÍČEK, P., CAPÁKOVÁ, Z., WRZECIONKO, E., SÁHA, P.

Released

23. 4. 2019

Publisher

The Royal Society of Chemistry

ISBN

2046-2069

Periodical

RSC Advances

Year of study

9

Number

1

State

United Kingdom of Great Britain and Northern Ireland

Pages from

12346

Pages to

12353

Pages count

8

URL

https://pubs.rsc.org/en/content/articlelanding/2019/ra/c8ra09757g#!divAbstract

Full text in the Digital Library

http://hdl.handle.net/11012/194738

BibTex

@article{BUT157312,
  author="Petra {Rejmontová} and Adriána {Kovalčík} and Petr {Humpolíček} and Zdenka {Capáková} and Erik {Wrzecionko} and Petr {Sáha}",
  title="The use of fractionated Kraft lignin to improve the mechanical and biological properties of PVA-based scaffolds",
  journal="RSC Advances",
  year="2019",
  volume="9",
  number="1",
  pages="12346--12353",
  doi="10.1039/C8RA09757G",
  issn="2046-2069",
  url="https://pubs.rsc.org/en/content/articlelanding/2019/ra/c8ra09757g#!divAbstract"
}

Documents

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