Publication detail

Analysis of chemotherapeutics in extracellular vesicles

KOŽNAROVÁ, S. ZELINOVÁ, K. VAŠINOVÁ GALIOVÁ, HRSTKA, R. VONKA, P M. COUFALÍK, P. ZVĚŘINA, O.

Original Title

Analysis of chemotherapeutics in extracellular vesicles

Type

conference proceedings

Language

English

Original Abstract

The ICP-MS method proved to be appropriate for further research on cell-to-cell communication. From our results we may conclude that the naturally resistant SK-OV-3 cell line probably uses the mechanism of chemotherapeutic drug excretion from the cells by exosomes. In comparison, A2780cis cells also seemed to secrete exosomes abundantly, but at the same time with lower influx efficiency. Based on this fact, it can be assumed that A2780cis has a different resistance mechanism compared to SK-OV-3.

Keywords

CANCER; CHEMOTHERAPEUTICS; EXOSOMES; ICP-MS

Authors

KOŽNAROVÁ, S.; ZELINOVÁ, K.; VAŠINOVÁ GALIOVÁ, HRSTKA, R.; VONKA, P; M.; COUFALÍK, P.; ZVĚŘINA, O.

Released

4. 9. 2022

ISBN

978-80-88195-41-2

Book

BOOK OF ABSTRACTS ESAS 2022

BibTex

@proceedings{BUT182195,
  editor="KOŽNAROVÁ, S. and ZELINOVÁ, K. and VAŠINOVÁ GALIOVÁ, HRSTKA, R. and VONKA, P and M. and COUFALÍK, P. and ZVĚŘINA, O.",
  title="Analysis of chemotherapeutics in extracellular vesicles",
  year="2022",
  isbn="978-80-88195-41-2"
}