Project detail

Antimicrobial Foams Based on Modified Polysaccharides for Accelerated Hemostasis: In Vivo Evaluation in a Rabbit Model Simulating Arterial Bleeding

Duration: 1.1.2026 — 31.12.2029

Funding resources

Ministerstvo zdravotnictví ČR - Program na podporu zdravotnického aplikovaného výzkumu na léta 2024 – 2030 - 3. VS

On the project

As medical treatment standards rise, so does the demand for innovative medical methods and materials. This project aims to develop an advanced foam hemostatic system with antimicrobial properties. The system will be evaluated using a rabbit carotid injury model for severe arterial bleeding and a standardized rabbit kidney damage model. The goal is to introduce a new hemostatic tool capable of controlling bleeding from severely damaged arteries and preventing infections. This innovation will enhance survival chances for critically injured patients in emergency situations, both civilian and military.

Keywords
antimicrobial activity; hemostatic; animal model; polysaccharides; hemorrhage

Mark

NW26J-06-00079

Default language

English

People responsible

Pavliňáková Veronika, Mgr., Ph.D. - principal person responsible
Dinparvar Sahar, Ph.D. - fellow researcher
Izsák Dávid, Ing. - fellow researcher
Sedlář Marian, Ing. - fellow researcher
Vojtová Lucy, doc. Ing., Ph.D. - fellow researcher

Units

Advanced Biomaterials
- responsible department (17.3.2025 - not assigned)
Advanced Biomaterials
- beneficiary (17.3.2025 - not assigned)