Detail aplikovaného výsledku

Process for making fingolimod

Reinerus Gerardus Gieling, Jozef Krajcovic

Original Title

Process for making fingolimod

English Title

Process for making fingolimod

Type

Patent

Original Abstract

The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a solvent with hydrogen in a presence of a hydrogenation catalyst, preferably palladium catalyst, and optionally converting fingolimod of formula (1) into an acidaddition salt, to compounds of formula (11) and (14) and their use in making fingolimod.

English abstract

The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a solvent with hydrogen in a presence of a hydrogenation catalyst, preferably palladium catalyst, and optionally converting fingolimod of formula (1) into an acidaddition salt, to compounds of formula (11) and (14) and their use in making fingolimod.

Patent number

WO2012041359A1

Date of application

01.10.2010

Date of registration

05.04.2012

Owner

SYNTHON B.V. Microweg 22 NL-6545 CM Nijmegen

Licence fee

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