Applied result detail
Process for making fingolimod
Reinerus Gerardus Gieling, Jozef Krajcovic
Original Title
Process for making fingolimod
English Title
Process for making fingolimod
Type
Patent
Original Abstract
The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a solvent with hydrogen in a presence of a hydrogenation catalyst, preferably palladium catalyst, and optionally converting fingolimod of formula (1) into an acidaddition salt, to compounds of formula (11) and (14) and their use in making fingolimod.
English abstract
The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a solvent with hydrogen in a presence of a hydrogenation catalyst, preferably palladium catalyst, and optionally converting fingolimod of formula (1) into an acidaddition salt, to compounds of formula (11) and (14) and their use in making fingolimod.
Patent number
WO2012041359A1
Date of application
01.10.2010
Date of registration
05.04.2012
Owner
SYNTHON B.V. Microweg 22 NL-6545 CM Nijmegen
Licence fee
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