Detail aplikovaného výsledku

Process for making fingolimod hydrochloride crystals

Jozef Krajcovic

Original Title

Process for making fingolimod hydrochloride crystals

English Title

Process for making fingolimod hydrochloride crystals

Type

Patent

Original Abstract

The invention relates to a process of making crystalline fingolimod hydrochloride of Formula (1a), comprising a step of contacting a solution of fingolimod hydrochloride in a solvent with an antisolvent at an enhanced temperature, and cooling such solution whereby crystalline fingolimod hydrochloride precipitates, and isolating crystalline fingolimod hydrochloride from the liquid medium.

English abstract

The invention relates to a process of making crystalline fingolimod hydrochloride of Formula (1a), comprising a step of contacting a solution of fingolimod hydrochloride in a solvent with an antisolvent at an enhanced temperature, and cooling such solution whereby crystalline fingolimod hydrochloride precipitates, and isolating crystalline fingolimod hydrochloride from the liquid medium.

Patent number

WO2012089238A1

Date of application

28.12.2010

Date of registration

05.06.2012

Owner

SYNTHON B.V. Microweg 22 NL-6545 CM Nijmegen

Licence fee

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