R&D result detail

Original Title

Preparation, characterization and cytotoxicity of schizophyllan/silvernanoparticle composite

English Title

Preparation, characterization and cytotoxicity of schizophyllan/silvernanoparticle composite

Type

WoS Article

Original Abstract

tSilver nanoparticles (Ag-NPs) have been successfully prepared with a simple and green chemical reduction method. Triple helical schizophyllan (SPG) was used for the first time as reducing and stabilizingagents. The effect of temperature, silver nitrate/schizophyllan concentrations, pH of the reactions mediumand the reaction time were investigated. The obtained schizophyllan/Ag-NP was characterized by UV–visspectroscopy, TEM, DLS, X-ray diffraction, TGA, and ATR-FTIR. The results revealed that, Ag-NPs attachedto SPG through a strong non-covalent interaction, leading to good dispersion of Ag-NPs with a diameterof 6 nm within the biopolymer matrix. By increasing the pH of the reaction medium, the triple helicalstructure of SPG was partially broken. The SPG/AgNP nanocomposite was non-toxic for mouse fibroblastline (NIH-3T3) and human keratinocyte cell line (HaCaT).

English abstract

tSilver nanoparticles (Ag-NPs) have been successfully prepared with a simple and green chemical reduction method. Triple helical schizophyllan (SPG) was used for the first time as reducing and stabilizingagents. The effect of temperature, silver nitrate/schizophyllan concentrations, pH of the reactions mediumand the reaction time were investigated. The obtained schizophyllan/Ag-NP was characterized by UV–visspectroscopy, TEM, DLS, X-ray diffraction, TGA, and ATR-FTIR. The results revealed that, Ag-NPs attachedto SPG through a strong non-covalent interaction, leading to good dispersion of Ag-NPs with a diameterof 6 nm within the biopolymer matrix. By increasing the pH of the reaction medium, the triple helicalstructure of SPG was partially broken. The SPG/AgNP nanocomposite was non-toxic for mouse fibroblastline (NIH-3T3) and human keratinocyte cell line (HaCaT).

Keywords

Silver, nanoparticles

Key words in English

Silver, nanoparticles

Authors

ABDEL-LATTIF, A.; ABDEL-RAHMAN, R.; FOUDA, M.; VOJTOVÁ, L.; UHROVÁ, L.; HASSAN, A.; AL-DEYAB, S.; EL-SHAMY, I.; JANČÁŘ, J.

RIV year

2015

Released

15.02.2014

ISBN

0144-8617

Periodical

Carbohydrate Polymers

Volume

102

Number

1

State

United Kingdom of Great Britain and Northern Ireland

Pages from

238

Pages to

245

Pages count

8

BibTex

@article{BUT104736,
  author="Abdelmohsen Moustafa {Abdellatif} and Rasha M. {Abdel-Rahman} and Moustafa M.D. {Fouda} and Lucy {Vojtová} and Lucie {Uhrová} and A.F. {Hassan} and Salem S. {Al-Deyab} and Ibrahim E. {El-Shamy} and Josef {Jančář}",
  title="Preparation, characterization and cytotoxicity of schizophyllan/silvernanoparticle composite",
  journal="Carbohydrate Polymers",
  year="2014",
  volume="102",
  number="1",
  pages="238--245",
  doi="10.1016/j.carbpol.2013.11.040",
  issn="0144-8617"
}