Detail publikačního výsledku
Reaction and Antibacterial Efficacy of Active Methylene Compounds with Coumarin Derivatives
SOLIMAN, A.; MOHAMED, F.; ABDEL-MOTALEB, R.; ABDEL-RAHMAN, R.; ABDEL-LATTIF, A.; FOUDA, M.; AL-DEYAB, S.; MOHAMED, A.
Original Title
Reaction and Antibacterial Efficacy of Active Methylene Compounds with Coumarin Derivatives
English Title
Reaction and Antibacterial Efficacy of Active Methylene Compounds with Coumarin Derivatives
Type
WoS Article
Original Abstract
2a,b, 3a,b ),(3 -acetyl-4-aryl -2-methyl-5-oxo-chromeno[3,2-c]2,3,4- trihydropyran 4a,b ), ( 2-amino-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile 5a,b and 2-amino-5-oxo-3,4,4a,10b-tetrahydro-2H,5H-pyrano[3,2-c]chromene-3-carboxylic acid amide 6a,b) were synthesized starting from 3-arylidene chromen-2,4-dione derivatives. The structures of the obtained compounds were confirmed by analytical elemental analysis, IR, 1H-NMR and mass spectra. The new compounds were screened for their antibacterial activity .Compound 3a was the most active compound against gram positive and gram negative bacteria.
English abstract
2a,b, 3a,b ),(3 -acetyl-4-aryl -2-methyl-5-oxo-chromeno[3,2-c]2,3,4- trihydropyran 4a,b ), ( 2-amino-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile 5a,b and 2-amino-5-oxo-3,4,4a,10b-tetrahydro-2H,5H-pyrano[3,2-c]chromene-3-carboxylic acid amide 6a,b) were synthesized starting from 3-arylidene chromen-2,4-dione derivatives. The structures of the obtained compounds were confirmed by analytical elemental analysis, IR, 1H-NMR and mass spectra. The new compounds were screened for their antibacterial activity .Compound 3a was the most active compound against gram positive and gram negative bacteria.
Keywords
antibacterial, synthesis, coumarin drerivatives, IR, NMR, MS
Key words in English
antibacterial, synthesis, coumarin drerivatives, IR, NMR, MS
Authors
SOLIMAN, A.; MOHAMED, F.; ABDEL-MOTALEB, R.; ABDEL-RAHMAN, R.; ABDEL-LATTIF, A.; FOUDA, M.; AL-DEYAB, S.; MOHAMED, A.
Released
01.11.2013
ISBN
0973-7510
Periodical
Journal of Pure and Applied Microbiology
Volume
7
Number
1
State
Republic of India
Pages from
435
Pages to
439
Pages count
5
Full text in the Digital Library
BibTex
@article{BUT106195,
author="A. Y. {Soliman} and F. K. {Mohamed} and Ramadan M. {Abdel-Motaleb} and Rasha M. {Abdel-Rahman} and Abdelmohsen Moustafa {Abdellatif} and Moustafa M.D. {Fouda} and Salem S. {Al-Deyab} and Asmaa S. {Mohamed}",
title="Reaction and Antibacterial Efficacy of Active Methylene Compounds with Coumarin Derivatives",
journal="Journal of Pure and Applied Microbiology",
year="2013",
volume="7",
number="1",
pages="435--439",
issn="0973-7510"
}