Detail publikačního výsledku

Synthesis and Antibacterial Activity of New Quinoline Derivatives Started from Coumarin Compounds

MOHAMED, F.; SOLIMAN, A.; ABDEL-MOTALEB, R.; ABDEL-RAHMAN, R.; ABDEL-LATTIF, A.; FOUDA, M.; AL-DEYAB, S.; HRDINA, R.

Original Title

Synthesis and Antibacterial Activity of New Quinoline Derivatives Started from Coumarin Compounds

English Title

Synthesis and Antibacterial Activity of New Quinoline Derivatives Started from Coumarin Compounds

Type

WoS Article

Original Abstract

An efficient synthetic method for the preparation of quinoline derivatives started from coumarin compounds was described. Fused coumarin derivative 1 reacted with amm acetate to afford 3-methylene-quinoline-2, 4-dione 2. In the same way active methylene compounds as ethyl acetoacetate, ethyl cyanoacetate, acetyl acetone and malonitrile reacted with compound 1 and gave the corresponding quinolines derivatives 3-6. All the newly compounds were characterized by elemental analysis, IR and mass spectra.

English abstract

An efficient synthetic method for the preparation of quinoline derivatives started from coumarin compounds was described. Fused coumarin derivative 1 reacted with amm acetate to afford 3-methylene-quinoline-2, 4-dione 2. In the same way active methylene compounds as ethyl acetoacetate, ethyl cyanoacetate, acetyl acetone and malonitrile reacted with compound 1 and gave the corresponding quinolines derivatives 3-6. All the newly compounds were characterized by elemental analysis, IR and mass spectra.

Keywords

Coumarin, Active methylene, Ammonium acetate, Quinoline, Antibacterial activity.

Key words in English

Coumarin, Active methylene, Ammonium acetate, Quinoline, Antibacterial activity.

Authors

MOHAMED, F.; SOLIMAN, A.; ABDEL-MOTALEB, R.; ABDEL-RAHMAN, R.; ABDEL-LATTIF, A.; FOUDA, M.; AL-DEYAB, S.; HRDINA, R.

RIV year

2014

Released

01.11.2013

ISBN

0973-7510

Periodical

Journal of Pure and Applied Microbiology

Volume

7

Number

1

State

Republic of India

Pages from

453

Pages to

458

Pages count

6

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@article{BUT106196,
  author="F. K. {Mohamed} and A. Y. {Soliman} and Ramadan M. {Abdel-Motaleb} and Rasha M. {Abdel-Rahman} and Abdelmohsen Moustafa {Abdellatif} and Moustafa M.D. {Fouda} and Salem S. {Al-Deyab} and Radim {Hrdina}",
  title="Synthesis and Antibacterial Activity of New Quinoline Derivatives Started from Coumarin Compounds",
  journal="Journal of Pure and Applied Microbiology",
  year="2013",
  volume="7",
  number="1",
  pages="453--458",
  issn="0973-7510"
}