Publication result detail
Mutant hyaluronan lyase sphyl lacking α-domain possesses catalytic activity
Stanislav Pepeliaev, Jana Jilkova, Radka Hrudikova, Dzianis Smirnou, Lukas Franke
Original Title
Mutant hyaluronan lyase sphyl lacking α-domain possesses catalytic activity
English Title
Mutant hyaluronan lyase sphyl lacking α-domain possesses catalytic activity
Type
Abstract
Original Abstract
The hyaluronan-digesting enzymes or hyaluronidases are the most widely represented and important among all hyaluronan-modifying enzymes. Hyaluronidases, a class of enzymes cleaving hyaluronan (HA), could be divided to the three groups according to their mechanism of cleavage. The mammalian hyaluronidases, which are endo-beta-N-acetylhexosaminidases, randomly cleave beta-1,4-glycosidei bonds in hyaluronic acid, chondroitin and chondroitin sulfate.
English abstract
The hyaluronan-digesting enzymes or hyaluronidases are the most widely represented and important among all hyaluronan-modifying enzymes. Hyaluronidases, a class of enzymes cleaving hyaluronan (HA), could be divided to the three groups according to their mechanism of cleavage. The mammalian hyaluronidases, which are endo-beta-N-acetylhexosaminidases, randomly cleave beta-1,4-glycosidei bonds in hyaluronic acid, chondroitin and chondroitin sulfate.
Keywords
Hyaluronan lyase, α-domain of enzyme, catalytic activity
Key words in English
Hyaluronan lyase, α-domain of enzyme, catalytic activity
Authors
Stanislav Pepeliaev, Jana Jilkova, Radka Hrudikova, Dzianis Smirnou, Lukas Franke
RIV year
2016
Released
08.10.2015
Publisher
Czech Chemical Society, Prague
Location
Prague, Czech Republic
ISBN
978-80-86238-85-2
Book
Proceedings of the 11th International Conference on Polysacharides-Glycoscience
Edition
1
ISBN
2336-6796
Periodical
Proceedings of the ... International Conference on Polysaccharides-Glycoscience
State
Czech Republic
Pages from
147
Pages to
150
Pages count
4
BibTex
@misc{BUT117410,
author="Radka {Hrudíková}",
title="Mutant hyaluronan lyase sphyl lacking α-domain possesses catalytic activity",
booktitle="Proceedings of the 11th International Conference on Polysacharides-Glycoscience",
year="2015",
series="1",
edition="1",
journal="Proceedings of the ... International Conference on Polysaccharides-Glycoscience",
pages="147--150",
publisher="Czech Chemical Society, Prague",
address="Prague, Czech Republic",
isbn="978-80-86238-85-2",
issn="2336-6796",
note="Abstract"
}