Detail publikačního výsledku
Effect of counterion on rheological properties of hydrogels prepared from hyaluronan and oppositely charged surfactant
VELCER, T.; PEKAŘ, M.
Original Title
Effect of counterion on rheological properties of hydrogels prepared from hyaluronan and oppositely charged surfactant
English Title
Effect of counterion on rheological properties of hydrogels prepared from hyaluronan and oppositely charged surfactant
Type
Paper in proceedings (conference paper)
Original Abstract
This study deals with the properties and behaviour of phase-separated hydrogels prepared by interaction of hyaluronan (Hya) with oppositely charged surfactants. Three representatives of surfactants, namely cetyltrimethylammonium bromide, chloride and p-toluensulfonate (CTAB, CTAC, CTAT), were selected for comparison. Using the method of rheology, the fact that the system of Hya-CTAT forms the most rigid hydrogels has been proved. Higher molecular weight of hyaluronan has also direct influence on the volume and stiffness of the newly formed hydrogels. Preparation methods were compared as well. Mixing the stock solutions of entry components appeard to be the most suitable. The results of this study indicate that given gels are to a certain extent competitive and incorporation of hyaluronan into their structure is desirable with respect to its biological activity. This offers a potential usage of these substances in the field of medical applications.
English abstract
This study deals with the properties and behaviour of phase-separated hydrogels prepared by interaction of hyaluronan (Hya) with oppositely charged surfactants. Three representatives of surfactants, namely cetyltrimethylammonium bromide, chloride and p-toluensulfonate (CTAB, CTAC, CTAT), were selected for comparison. Using the method of rheology, the fact that the system of Hya-CTAT forms the most rigid hydrogels has been proved. Higher molecular weight of hyaluronan has also direct influence on the volume and stiffness of the newly formed hydrogels. Preparation methods were compared as well. Mixing the stock solutions of entry components appeard to be the most suitable. The results of this study indicate that given gels are to a certain extent competitive and incorporation of hyaluronan into their structure is desirable with respect to its biological activity. This offers a potential usage of these substances in the field of medical applications.
Keywords
hyaluronan, surfactants, hydrogels, rheology
Key words in English
hyaluronan, surfactants, hydrogels, rheology
Authors
VELCER, T.; PEKAŘ, M.
RIV year
2018
Released
23.03.2017
Publisher
Vysoké učení technické v Brně, Fakulta chemická
Location
Brno
ISBN
978-80-214-5489-7
Book
Sborník příspěvků
Edition
1.
Pages from
218
Pages to
223
Pages count
6
Full text in the Digital Library
BibTex
@inproceedings{BUT140071,
author="Tomáš {Velcer} and Miloslav {Pekař}",
title="Effect of counterion on rheological properties of hydrogels prepared from hyaluronan and oppositely charged surfactant",
booktitle="Sborník příspěvků",
year="2017",
series="1.",
number="první",
pages="218--223",
publisher="Vysoké učení technické v Brně, Fakulta chemická",
address="Brno",
isbn="978-80-214-5489-7"
}