Publication result detail
Novel unexpected functions of PHA granules
OBRUČA, S.; SEDLÁČEK, P.; SLANINOVÁ, E.; FRITZ, I.; DAFFERT, C.; MEIXNER, K.; ŠEDRLOVÁ, Z.; KOLLER, M.
Original Title
Novel unexpected functions of PHA granules
English Title
Novel unexpected functions of PHA granules
Type
WoS Article
Original Abstract
Polyhydroxyalkanoates (PHA), polyesters accumulated by numerous prokaryotes in the form of intracellular granules, have been for decades considered being predominantly storage molecules. However, numerous recent discoveries revealed and emphasized their complex biological role for microbial cells. Most of all, it was repeatedly reported and confirmed that the presence of PHA granules in prokaryotic cells enhances stress resistance and robustness of microbes against various environmental stress factors such as high or low temperature, freezing, oxidative, and osmotic pressure. It seems that protective mechanisms of PHA granules are associated with their extraordinary architecture and biophysical properties as well as with the complex and deeply interconnected nature of PHA metabolism. Therefore, this review aims at describing novel and unexpected properties of PHA granules with respect to their contribution to stress tolerance of various prokaryotes including common mesophilic heterotrophic bacteria, but also extremophiles or photo-autotrophic cyanobacteria.
English abstract
Polyhydroxyalkanoates (PHA), polyesters accumulated by numerous prokaryotes in the form of intracellular granules, have been for decades considered being predominantly storage molecules. However, numerous recent discoveries revealed and emphasized their complex biological role for microbial cells. Most of all, it was repeatedly reported and confirmed that the presence of PHA granules in prokaryotic cells enhances stress resistance and robustness of microbes against various environmental stress factors such as high or low temperature, freezing, oxidative, and osmotic pressure. It seems that protective mechanisms of PHA granules are associated with their extraordinary architecture and biophysical properties as well as with the complex and deeply interconnected nature of PHA metabolism. Therefore, this review aims at describing novel and unexpected properties of PHA granules with respect to their contribution to stress tolerance of various prokaryotes including common mesophilic heterotrophic bacteria, but also extremophiles or photo-autotrophic cyanobacteria.
Keywords
Bacteria; Polyhydroxyalkanoates; PHA granules; Stress robustness; Cupriavidus necator; Extremophiles; Cyanobacteria
Key words in English
Bacteria; Polyhydroxyalkanoates; PHA granules; Stress robustness; Cupriavidus necator; Extremophiles; Cyanobacteria
Authors
OBRUČA, S.; SEDLÁČEK, P.; SLANINOVÁ, E.; FRITZ, I.; DAFFERT, C.; MEIXNER, K.; ŠEDRLOVÁ, Z.; KOLLER, M.
RIV year
2021
Released
01.06.2020
Publisher
Springer
ISBN
0175-7598
Periodical
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume
104
Number
11
State
Federal Republic of Germany
Pages from
4795
Pages to
4810
Pages count
16
URL
BibTex
@article{BUT164177,
author="OBRUČA, S. and SEDLÁČEK, P. and SLANINOVÁ, E. and FRITZ, I. and DAFFERT, C. and MEIXNER, K. and ŠEDRLOVÁ, Z. and KOLLER, M.",
title="Novel unexpected functions of PHA granules",
journal="APPLIED MICROBIOLOGY AND BIOTECHNOLOGY",
year="2020",
volume="104",
number="11",
pages="4795--4810",
doi="10.1007/s00253-020-10568-1",
issn="0175-7598",
url="https://link.springer.com/article/10.1007/s00253-020-10568-1"
}Documents