Detail publikačního výsledku
The underexplored role of diverse stress factors in microbial biopolymer synthesis
OBRUČA, S.; SEDLÁČEK, P.; KOLLER, M.
Original Title
The underexplored role of diverse stress factors in microbial biopolymer synthesis
English Title
The underexplored role of diverse stress factors in microbial biopolymer synthesis
Type
WoS Article
Original Abstract
Polyhydroxyalkanoates (PHA) are microbial polyesters which, apart from their primary storage role, enhance the stress robustness of PHA accumulating cells against various stressors. PHA also represent interesting alternatives to petrochemical polymers, which can be produced from renewable resources employing approaches of microbial biotechnology. During biotechnological processes, bacterial cells are exposed to various stressor factors such as fluctuations in temperature, osmolarity, pH-value, elevated pressure or the presence of microbial inhibitors. This review summarizes how PHA helps microbial cells to cope with biotechnological process-relevant stressors and, vice versa, how various stress conditions can affect PHA production processes. The review suggests a fundamentally new strategy for PHA production: the fine-tuned exposure to selected stressors, which might be used to boost PHA production and even to tailor their structure.
English abstract
Polyhydroxyalkanoates (PHA) are microbial polyesters which, apart from their primary storage role, enhance the stress robustness of PHA accumulating cells against various stressors. PHA also represent interesting alternatives to petrochemical polymers, which can be produced from renewable resources employing approaches of microbial biotechnology. During biotechnological processes, bacterial cells are exposed to various stressor factors such as fluctuations in temperature, osmolarity, pH-value, elevated pressure or the presence of microbial inhibitors. This review summarizes how PHA helps microbial cells to cope with biotechnological process-relevant stressors and, vice versa, how various stress conditions can affect PHA production processes. The review suggests a fundamentally new strategy for PHA production: the fine-tuned exposure to selected stressors, which might be used to boost PHA production and even to tailor their structure.
Keywords
Biotechnological process; Hormesis; Polyhydroxyalkanoates; Stress conditions; Waste substrates
Key words in English
Biotechnological process; Hormesis; Polyhydroxyalkanoates; Stress conditions; Waste substrates
Authors
OBRUČA, S.; SEDLÁČEK, P.; KOLLER, M.
RIV year
2021
Released
01.04.2021
Publisher
ELSEVIER SCI LTD
Location
Oxford
ISBN
0960-8524
Periodical
BIORESOURCE TECHNOLOGY
Volume
326
Number
4
State
Kingdom of the Netherlands
Pages from
1
Pages to
12
Pages count
12
URL
Full text in the Digital Library
BibTex
@article{BUT170832,
author="Stanislav {Obruča} and Petr {Sedláček} and Martin {Koller}",
title="The underexplored role of diverse stress factors in microbial biopolymer synthesis",
journal="BIORESOURCE TECHNOLOGY",
year="2021",
volume="326",
number="4",
pages="1--12",
doi="10.1016/j.biortech.2021.124767",
issn="0960-8524",
url="https://www.sciencedirect.com/science/article/pii/S0960852421001061"
}Documents