Publication result detail
Rhodotorula kratochvilovae CCY 20-2-26-The Source of Multifunctional Metabolites
BYRTUSOVÁ, D.; SZOTKOWSKI, M.; KUROWSKA, K.; SHAPAVAL, V.; MÁROVÁ, I.
Original Title
Rhodotorula kratochvilovae CCY 20-2-26-The Source of Multifunctional Metabolites
English Title
Rhodotorula kratochvilovae CCY 20-2-26-The Source of Multifunctional Metabolites
Type
WoS Article
Original Abstract
Multifunctional biomass is able to provide more than one valuable product, and thus, it is attractive in the field of microbial biotechnology due to its economic feasibility. Carotenogenic yeasts are effective microbial factories for the biosynthesis of a broad spectrum of biomolecules that can be used in the food and feed industry and the pharmaceutical industry, as well as a source of biofuels. In the study, we examined the effect of different nitrogen sources, carbon sources and CN ratios on the co-production of intracellular lipids, carotenoids, beta-glucans and extracellular glycolipids. Yeast strain R. kratochvilovae CCY 20-2-26 was identified as the best co-producer of lipids (66.7 +/- 1.5% of DCW), exoglycolipids (2.42 +/- 0.08 g/L), beta-glucan (11.33 +/- 1.34% of DCW) and carotenoids (1.35 +/- 0.11 mg/g), with a biomass content of 15.2 +/- 0.8 g/L, by using the synthetic medium with potassium nitrate and mannose as a carbon source. It was shown that an increased C/N ratio positively affected the biomass yield and production of lipids and beta-glucans.
English abstract
Multifunctional biomass is able to provide more than one valuable product, and thus, it is attractive in the field of microbial biotechnology due to its economic feasibility. Carotenogenic yeasts are effective microbial factories for the biosynthesis of a broad spectrum of biomolecules that can be used in the food and feed industry and the pharmaceutical industry, as well as a source of biofuels. In the study, we examined the effect of different nitrogen sources, carbon sources and CN ratios on the co-production of intracellular lipids, carotenoids, beta-glucans and extracellular glycolipids. Yeast strain R. kratochvilovae CCY 20-2-26 was identified as the best co-producer of lipids (66.7 +/- 1.5% of DCW), exoglycolipids (2.42 +/- 0.08 g/L), beta-glucan (11.33 +/- 1.34% of DCW) and carotenoids (1.35 +/- 0.11 mg/g), with a biomass content of 15.2 +/- 0.8 g/L, by using the synthetic medium with potassium nitrate and mannose as a carbon source. It was shown that an increased C/N ratio positively affected the biomass yield and production of lipids and beta-glucans.
Keywords
Rhodotorula kratochvilovae; lipids; extracellular glycolipids; carotenoids; beta-glucan
Key words in English
Rhodotorula kratochvilovae; lipids; extracellular glycolipids; carotenoids; beta-glucan
Authors
BYRTUSOVÁ, D.; SZOTKOWSKI, M.; KUROWSKA, K.; SHAPAVAL, V.; MÁROVÁ, I.
RIV year
2022
Released
11.07.2021
Publisher
MDPI
Location
BASEL
ISBN
2076-2607
Periodical
Microorganisms
Volume
9
Number
6
State
Swiss Confederation
Pages from
1
Pages to
18
Pages count
18
URL
Full text in the Digital Library
BibTex
@article{BUT172746,
author="Dana {Byrtusová} and Martin {Szotkowski} and Klára {Kurowska} and Volha {Shapaval} and Ivana {Márová}",
title="Rhodotorula kratochvilovae CCY 20-2-26-The Source of Multifunctional Metabolites",
journal="Microorganisms",
year="2021",
volume="9",
number="6",
pages="1--18",
doi="10.3390/microorganisms9061280",
url="https://www.mdpi.com/2076-2607/9/6/1280"
}Documents