Publication result detail
Nebulizer particle size distribution measured by various methods
MIŠÍK, O.; PEŠTÁLOVÁ, A.; BĚLKA, M.; LÍZAL, F.
Original Title
Nebulizer particle size distribution measured by various methods
English Title
Nebulizer particle size distribution measured by various methods
Type
Paper in proceedings outside WoS and Scopus
Original Abstract
Pari LC Sprint Star nebulizer is an inhaler device dedicated to delivering the liquid drug formulation into peripheral lung regions. The particle size is one of the critical parameters which determine the location of aerosol deposition within the human lungs. In this study, the particle size distribution of aerosol was measured by two different methods: Andersen Cascade Impactor (ACI) and Aerodynamic Particle Sizer (APS). Mass Median of Aerodynamic Distribution (MMAD), and Geometric Standard Deviation (GSD) were evaluated. MMAD gained by APS was approx. 7 μm, MMAD acquired by ACI was approx. 2.5 μm. According to the results, these two measuring methods are not very consistent, and the comparison of the particle size acquired by the different methods is not appropriate.
English abstract
Pari LC Sprint Star nebulizer is an inhaler device dedicated to delivering the liquid drug formulation into peripheral lung regions. The particle size is one of the critical parameters which determine the location of aerosol deposition within the human lungs. In this study, the particle size distribution of aerosol was measured by two different methods: Andersen Cascade Impactor (ACI) and Aerodynamic Particle Sizer (APS). Mass Median of Aerodynamic Distribution (MMAD), and Geometric Standard Deviation (GSD) were evaluated. MMAD gained by APS was approx. 7 μm, MMAD acquired by ACI was approx. 2.5 μm. According to the results, these two measuring methods are not very consistent, and the comparison of the particle size acquired by the different methods is not appropriate.
Keywords
aerosol, nebulizer, particle size, andersen cascade impactor, aerodynamic particle sizer
Key words in English
aerosol, nebulizer, particle size, andersen cascade impactor, aerodynamic particle sizer
Authors
MIŠÍK, O.; PEŠTÁLOVÁ, A.; BĚLKA, M.; LÍZAL, F.
RIV year
2022
Released
26.11.2021
Location
Liberec
Pages from
119
Pages to
122
Pages count
4
Full text in the Digital Library
BibTex
@inproceedings{BUT174901,
author="Ondrej {Mišík} and Andrea {Peštálová} and Miloslav {Bělka} and František {Lízal}",
title="Nebulizer particle size distribution measured by various methods",
year="2021",
pages="119--122",
address="Liberec"
}