Publication detail

Biotechnological production of polyhydroxyalkanoates from glycerol: A review

KOLLER, M. OBRUČA, S.

Original Title

Type

journal article in Web of Science

Language

English

Original Abstract

Current worldwide threats related to global warming, climate change, and depletion of limited fossil resources necessitate the switch of industry towards producing carbon-neutral chemicals, solvents, fuels, and plastics. In this context, biotechnology offers alternatives to established plastics from petrochemistry, namely microbial polyhydroxyalkanoate (PHA) biopolyesters. PHA, circular in their nature, span a broad range of material properties, which can be finetuned by the biotechnological production strategy; this way, PHA can mimic both thermoplastics and elastomers from petrochemistry. However, it's the still high production costs that impede the ultimate market penetration of PHA to replace established recalcitrant types of plastics. Selecting inexpensive waste and surplus materials from diverse industrial sectors for being used as biotechnological feedstocks for the production of PHA is among the most auspicious steps to increase PHA's competitiveness with petrochemical plastics. In this context, glycerol, an abundant carbonaceous side stream from steadily increasing biodiesel production, is among the globally emerging inexpensive materials for this purpose. The review article at hand provides an overview of how the renewable, high-volume, low-value resource glycerol can be converted by most diverse prokaryotic production strains to PHA of different structure and properties and highlights obstacles and particular benefits when using this waste stream for biopolyesters synthesis, with special emphasis dedicated to most recent developments, and the application of naturally occurring organisms (wild type strains) isolated from most diverse habitats.

Keywords

necator DSM 545; Cupriavidus-necator; poly(3-hydroxybutyrate) production; Pseudomonas-putida; Ralstonia-eutropha; crude glycerol; waste glycerol; transcriptome analysis; biodiesel production; agricultural waste

Authors

KOLLER, M.; OBRUČA, S.

Released

1. 7. 2022

Publisher

Elsevier

ISBN

1878-8181

Periodical

Biocatalysis and Agricultural Biotechnology

Year of study

Number

State

Kingdom of the Netherlands

Pages from

Pages to

Pages count

URL

https://www.sciencedirect.com/science/article/pii/S1878818122000603

Full text in the Digital Library

http://hdl.handle.net/11012/208205

BibTex

@article{BUT178524,
  author="Martin {Koller} and Stanislav {Obruča}",
  title="Biotechnological production of polyhydroxyalkanoates from glycerol: A review",
  journal="Biocatalysis and Agricultural Biotechnology",
  year="2022",
  volume="42",
  number="6",
  pages="1--31",
  doi="10.1016/j.bcab.2022.102333",
  issn="1878-8181",
  url="https://www.sciencedirect.com/science/article/pii/S1878818122000603"
}