Publication result detail

Synergistic performance of collagen-g-chitosan-glucan fiber biohybrid scaffold with tunable properties

ABDEL-RAHMAN, R.; VISHAKHA, V.; KELNAR, I.; JANČÁŘ, J.; ABDELLATIF, A.

Original Title

Synergistic performance of collagen-g-chitosan-glucan fiber biohybrid scaffold with tunable properties

English Title

Synergistic performance of collagen-g-chitosan-glucan fiber biohybrid scaffold with tunable properties

Type

WoS Article

Original Abstract

Hybrid biocomposite scaffolds (HBS) that serve as a carrier for cell proliferation and differentiation are increasingly used for tissue regeneration. 3D hybrid scaffold based on collagen-grafted-chitosan-glucan fiber (CO-g-CGF-HBS) was prepared by freeze-drying technique. The swelling percentage, hydrolytic stability, and modulus of elasticity of HBS were enhanced after the chemical modification of CO with CGF. Pore size and porosity of HBS were decreased with an increased CGF ratio. HBS exhibits a higher reduction rate against different types of bacteria compared with a control sample. Thus, chemical modification of CO with different ratios of CGF significantly improved the physicochemical, antibacterial properties of HBS.

English abstract

Hybrid biocomposite scaffolds (HBS) that serve as a carrier for cell proliferation and differentiation are increasingly used for tissue regeneration. 3D hybrid scaffold based on collagen-grafted-chitosan-glucan fiber (CO-g-CGF-HBS) was prepared by freeze-drying technique. The swelling percentage, hydrolytic stability, and modulus of elasticity of HBS were enhanced after the chemical modification of CO with CGF. Pore size and porosity of HBS were decreased with an increased CGF ratio. HBS exhibits a higher reduction rate against different types of bacteria compared with a control sample. Thus, chemical modification of CO with different ratios of CGF significantly improved the physicochemical, antibacterial properties of HBS.

Keywords

Hybrid scaffolds; Collagen; Chitosan-glucan fiber; Antibacterial and mechanical properties

Key words in English

Hybrid scaffolds; Collagen; Chitosan-glucan fiber; Antibacterial and mechanical properties

Authors

ABDEL-RAHMAN, R.; VISHAKHA, V.; KELNAR, I.; JANČÁŘ, J.; ABDELLATIF, A.

RIV year

2023

Released

31.03.2022

Publisher

ELSEVIER

Location

AMSTERDAM

ISBN

1879-0003

Periodical

International Journal of Biological Macromolecules

Volume

202

Number

1

State

Kingdom of the Netherlands

Pages from

671

Pages to

680

Pages count

10

URL

https://www.sciencedirect.com/science/article/pii/S0141813022000058?via%3Dihub

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@article{BUT178578,
  author="Reda M. {Abdel-Rahman} and Vishakha {Vishakha} and Ivan {Kelnar} and Josef {Jančář} and Abdelmohsen Moustafa {Abdellatif}",
  title="Synergistic performance of collagen-g-chitosan-glucan fiber biohybrid scaffold with tunable properties",
  journal="International Journal of Biological Macromolecules",
  year="2022",
  volume="202",
  number="1",
  pages="671--680",
  doi="10.1016/j.ijbiomac.2022.01.004",
  issn="0141-8130",
  url="https://www.sciencedirect.com/science/article/pii/S0141813022000058?via%3Dihub"
}