Detail publikačního výsledku
Feature-overlapper: The tool for DNA analysis overlap
HAVLÍK, J.; BRÁZDA, V.; STANĚK, K.; JEŽEK, M.; ŠŤASTNÝ, J.
Original Title
Feature-overlapper: The tool for DNA analysis overlap
English Title
Feature-overlapper: The tool for DNA analysis overlap
Type
WoS Article
Original Abstract
This contribution puts focus on a command line tool, which enables detection and analysis of overlapping regions between G-quadruplexes, R-loops and genome annotations for selected genomes. G-quadruplexes and R-loops are structures with high Guanine density, which is an important creation factor for both structures. Common regions (overlap) between both structures can provide us with better possibility to create precise model to detect R-loops and valuable insights when inspecting genome annotations with high R-loop density. The tool was used for multiple research projects and is under constant development bringing new features to the world of bioinformatics.
English abstract
This contribution puts focus on a command line tool, which enables detection and analysis of overlapping regions between G-quadruplexes, R-loops and genome annotations for selected genomes. G-quadruplexes and R-loops are structures with high Guanine density, which is an important creation factor for both structures. Common regions (overlap) between both structures can provide us with better possibility to create precise model to detect R-loops and valuable insights when inspecting genome annotations with high R-loop density. The tool was used for multiple research projects and is under constant development bringing new features to the world of bioinformatics.
Keywords
DNA; R-loop; G-quadruplex; Annotation
Key words in English
DNA; R-loop; G-quadruplex; Annotation
Authors
HAVLÍK, J.; BRÁZDA, V.; STANĚK, K.; JEŽEK, M.; ŠŤASTNÝ, J.
RIV year
2024
Released
01.05.2023
Publisher
Elsevier
Location
AMSTERDAM
ISBN
2665-9638
Periodical
Software Impacts
Volume
16
Number
5
State
Kingdom of the Netherlands
Pages from
1
Pages to
4
Pages count
4
URL
Full text in the Digital Library
BibTex
@article{BUT183463,
author="Jan {Havlík} and Václav {Brázda} and Kamil {Staněk} and Michal {Ježek} and Jiří {Šťastný}",
title="Feature-overlapper: The tool for DNA analysis overlap",
journal="Software Impacts",
year="2023",
volume="16",
number="5",
pages="1--4",
doi="10.1016/j.simpa.2023.100498",
issn="2665-9638",
url="https://www.sciencedirect.com/science/article/pii/S2665963823000350?via%3Dihub"
}Documents