Publication result detail

The study of adhesion and proliferation of cells on 3D printed PHB/PLA surfaces – the influence of surface roughness and wetting characteristics

KROBOT, Š.; MELČOVÁ, V.; PŘIKRYL, R.

Original Title

The study of adhesion and proliferation of cells on 3D printed PHB/PLA surfaces – the influence of surface roughness and wetting characteristics

English Title

The study of adhesion and proliferation of cells on 3D printed PHB/PLA surfaces – the influence of surface roughness and wetting characteristics

Type

Abstract

Original Abstract

This study aims to investigate how the surface characteristics of 3D printed scaffolds influence their suitability for supporting the growth of Saos-2 cells. Two materials, both composed of PHB/PLA plasticized blend, were studied. One of them also incorporating bioactive tricalcium phosphate (TCP). 3D printed surfaces demonstrated a notable increase in water contact angle (WCA) due to enhanced surface roughness. These alterations in wetting properties strongly impacted the behaviour of Saos-2 cells on the printed surfaces.

English abstract

This study aims to investigate how the surface characteristics of 3D printed scaffolds influence their suitability for supporting the growth of Saos-2 cells. Two materials, both composed of PHB/PLA plasticized blend, were studied. One of them also incorporating bioactive tricalcium phosphate (TCP). 3D printed surfaces demonstrated a notable increase in water contact angle (WCA) due to enhanced surface roughness. These alterations in wetting properties strongly impacted the behaviour of Saos-2 cells on the printed surfaces.

Keywords

3D printing; FDM; poly(3-hydroxybutyrate); bone tissue engineering; scaffold; biocompatibility; polylactic acid; water contact angle; surface roughness

Key words in English

3D printing; FDM; poly(3-hydroxybutyrate); bone tissue engineering; scaffold; biocompatibility; polylactic acid; water contact angle; surface roughness

Authors

KROBOT, Š.; MELČOVÁ, V.; PŘIKRYL, R.

Released

30.11.2023

Publisher

Vysoké učení technické v Brně, Fakulta chemická

Location

Purkyňova 464/118, 612 00 Brno

ISBN

978-80-214-6204-5

Book

Sborník abstraktů ze studentské odborné konference "Chemie je život 2023"

Pages from

84

Pages to

84

Pages count

1

URL

https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstraktu-2023-na-web-pdf-p251584

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@misc{BUT186924,
  author="Štěpán {Krobot} and Veronika {Odehnalová} and Radek {Přikryl}",
  title="The study of adhesion and proliferation of cells on 3D printed PHB/PLA surfaces – the influence of surface roughness and wetting characteristics",
  booktitle="Sborník abstraktů ze studentské odborné konference {"}Chemie je život 2023{"}",
  year="2023",
  edition="první",
  pages="84--84",
  publisher="Vysoké učení technické v Brně, Fakulta chemická",
  address="Purkyňova 464/118, 612 00 Brno",
  isbn="978-80-214-6204-5",
  url="https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstraktu-2023-na-web-pdf-p251584",
  note="Abstract"
}