Publication result detail
Isoprostanes as markers of oxidative stress
BOLECHOVÁ, M.; ČÁSLAVSKÝ, J.; VÁVROVÁ, M.
Original Title
Isoprostanes as markers of oxidative stress
English Title
Isoprostanes as markers of oxidative stress
Type
Abstract
Original Abstract
Oxidative stress is an imbalance between oxidants occurence on organism and its antioxidant defense. Oxidative stress is assessed by determination of secondary products like isoprostanes which is group of prostaglandin-like compounds. These are formed via non enzymatic radical oxidation of polyunsaturated fatty acids with at least four double bonds. One of the most useful method is determination of isoprostanes by HPLC with tandem mass spectrometric detection (HPLC-MS/MS).
English abstract
Oxidative stress is an imbalance between oxidants occurence on organism and its antioxidant defense. Oxidative stress is assessed by determination of secondary products like isoprostanes which is group of prostaglandin-like compounds. These are formed via non enzymatic radical oxidation of polyunsaturated fatty acids with at least four double bonds. One of the most useful method is determination of isoprostanes by HPLC with tandem mass spectrometric detection (HPLC-MS/MS).
Keywords
oxidative stress, fatty acids, isoprostanes, chromatography, mass spectrometry
Key words in English
oxidative stress, fatty acids, isoprostanes, chromatography, mass spectrometry
Authors
BOLECHOVÁ, M.; ČÁSLAVSKÝ, J.; VÁVROVÁ, M.
RIV year
2012
Released
17.08.2011
ISBN
0009-2770
Periodical
CHEMICKE LISTY
Volume
105
Number
18
State
Czech Republic
Pages from
959
Pages to
959
Pages count
1
BibTex
@misc{BUT35347,
author="Martina {Čumová} and Josef {Čáslavský} and Milada {Vávrová}",
title="Isoprostanes as markers of oxidative stress",
year="2011",
journal="CHEMICKE LISTY",
volume="105",
number="18",
pages="959--959",
issn="0009-2770",
note="Abstract"
}