Publication result detail
Suitability of extraction methods for determination of drug residues in the river sediment
ŽENATOVÁ, P.; VÁVROVÁ, M.; DADÁKOVÁ, P.
Original Title
Suitability of extraction methods for determination of drug residues in the river sediment
English Title
Suitability of extraction methods for determination of drug residues in the river sediment
Type
Abstract
Original Abstract
In this study, three different methods for extraction drug residues from river sediments were tested. Sulphonamide antibiotics, which belong to a group of pharmaceuticals widely used in human and veterinary medicine were selected as target compounds. They are discharged to the sewer systems together with the urine and faeces and enter to the wastewater treatment plant, where they are not completely removed. Their further negative impact on the ecosystem cannot therefore be excluded. Sulphonamide antibiotics were isolated from sample of river sediment by three different methods: ultrasonic extraction (USE), pressurized solvent extraction (PSE) and microwave-assisted extraction techniques (MAE). These three methods were compared and the most suitable method was found. Samples were concentrated and cleaned using solid phase extraction (SPE). For determination these antibiotics high performance liquid chromatography with diode array detector was used.
English abstract
In this study, three different methods for extraction drug residues from river sediments were tested. Sulphonamide antibiotics, which belong to a group of pharmaceuticals widely used in human and veterinary medicine were selected as target compounds. They are discharged to the sewer systems together with the urine and faeces and enter to the wastewater treatment plant, where they are not completely removed. Their further negative impact on the ecosystem cannot therefore be excluded. Sulphonamide antibiotics were isolated from sample of river sediment by three different methods: ultrasonic extraction (USE), pressurized solvent extraction (PSE) and microwave-assisted extraction techniques (MAE). These three methods were compared and the most suitable method was found. Samples were concentrated and cleaned using solid phase extraction (SPE). For determination these antibiotics high performance liquid chromatography with diode array detector was used.
Keywords
drug residua, water sediment, extraction methods, liquid chromatography
Key words in English
drug residua, water sediment, extraction methods, liquid chromatography
Authors
ŽENATOVÁ, P.; VÁVROVÁ, M.; DADÁKOVÁ, P.
RIV year
2012
Released
17.08.2011
Publisher
Fakulta chemická VUT Brno
Location
Brno
Book
5th Meeting on Chemistry and Life
ISBN
0009-2770
Periodical
CHEMICKE LISTY
Volume
105
Number
18
State
Czech Republic
Pages from
s974
Pages to
s974
Pages count
1