Detail publikačního výsledku
Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions
MRAVEC, F.; KLUČÁKOVÁ, M.; PEKAŘ, M.
Original Title
Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions
English Title
Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions
Type
Chapter in a book
Original Abstract
Capability of phospholipids with positive charge to form complexes with hyaluronan in aqueous solutions, in a similar way as traditional cationic surfactants, was investigated by fluorescence probes. DPPC and lecithin aggregate in aqueous solution to form micelle-like structures capable to solubilize hydrophobic molecules. Changes in aggregation behavior after adding hyaluronan were observed only in the case of lecithin. Further, non-ionic biocompatible surfactant was used as additional dispersion environment in phospholipid-hyaluronan system with phospholipid molecules acting as a physical linker bonding micelles and biopolymer.
English abstract
Capability of phospholipids with positive charge to form complexes with hyaluronan in aqueous solutions, in a similar way as traditional cationic surfactants, was investigated by fluorescence probes. DPPC and lecithin aggregate in aqueous solution to form micelle-like structures capable to solubilize hydrophobic molecules. Changes in aggregation behavior after adding hyaluronan were observed only in the case of lecithin. Further, non-ionic biocompatible surfactant was used as additional dispersion environment in phospholipid-hyaluronan system with phospholipid molecules acting as a physical linker bonding micelles and biopolymer.
Keywords
fluorescence probe, hyaluronan, interactions, phospholipid
Key words in English
fluorescence probe, hyaluronan, interactions, phospholipid
Authors
MRAVEC, F.; KLUČÁKOVÁ, M.; PEKAŘ, M.
RIV year
2012
Released
01.10.2011
Publisher
Academic Press
Location
Burlington
ISBN
978-0-12-387720-8
Book
Advances in Planar Lipid Bilayers and Liposomes
Edition
není
Pages from
235
Pages to
255
Pages count
21
Full text in the Digital Library
BibTex
@inbook{BUT74322,
author="Filip {Mravec} and Martina {Klučáková} and Miloslav {Pekař}",
title="Fluorescence Spectroscopy Study of Hyaluronan-Phospholipid Interactions",
booktitle="Advances in Planar Lipid Bilayers and Liposomes",
year="2011",
publisher="Academic Press",
address="Burlington",
series="není",
edition="14",
pages="235--255",
isbn="978-0-12-387720-8"
}