Detail publikačního výsledku

STABILITY OF THE COMPLEX NANOPARTICLES OF NEGATIVELY CHARGED HYALURONAN AND CATIONIC SURFACTANT

PILGROVÁ, T.; PEKAŘ, M.

Original Title

STABILITY OF THE COMPLEX NANOPARTICLES OF NEGATIVELY CHARGED HYALURONAN AND CATIONIC SURFACTANT

English Title

STABILITY OF THE COMPLEX NANOPARTICLES OF NEGATIVELY CHARGED HYALURONAN AND CATIONIC SURFACTANT

Type

Paper in proceedings (conference paper)

Original Abstract

The aim of our study was to prepare hyaluronic acid nanoparticles based on electrostatic interactions with oppositely charged molecules and study stability of these particles under different conditions. Time and temperature stability, effect of ionic strength, effect of dilution of the system and effect of molecular weight of hyaluronan were investigated using fluorescence spectroscopy and dynamic light scattering methods. Fluorescence and dynamic light scattering experiments indicate that hyaluronan-surfactant nanoparticles are influenced by a whole range of aspects, such as temperature, ionic strength of solution and storage time while molecular weight of hyaluronan affect these system at least.

English abstract

The aim of our study was to prepare hyaluronic acid nanoparticles based on electrostatic interactions with oppositely charged molecules and study stability of these particles under different conditions. Time and temperature stability, effect of ionic strength, effect of dilution of the system and effect of molecular weight of hyaluronan were investigated using fluorescence spectroscopy and dynamic light scattering methods. Fluorescence and dynamic light scattering experiments indicate that hyaluronan-surfactant nanoparticles are influenced by a whole range of aspects, such as temperature, ionic strength of solution and storage time while molecular weight of hyaluronan affect these system at least.

Keywords

Hyaluronan, surfactant, stability, fluorescence spectroscopy, dynamic light scattering

Key words in English

Hyaluronan, surfactant, stability, fluorescence spectroscopy, dynamic light scattering

Authors

PILGROVÁ, T.; PEKAŘ, M.

Released

05.11.2014

Publisher

Tanger Ltd.

Location

Ostrava

ISBN

978-80-87294-55-0

Book

NANOCON 2014, Conference Proceedings

Edition

1st edition, 2014

Pages from

1

Pages to

5

Pages count

5

Full text in the Digital Library

BibTex

@inproceedings{BUT110358,
  author="Tereza {Pilgrová} and Miloslav {Pekař}",
  title="STABILITY OF THE COMPLEX NANOPARTICLES OF NEGATIVELY CHARGED HYALURONAN AND CATIONIC SURFACTANT",
  booktitle="NANOCON 2014, Conference Proceedings",
  year="2014",
  series="1st edition, 2014",
  pages="1--5",
  publisher="Tanger Ltd.",
  address="Ostrava",
  isbn="978-80-87294-55-0"
}