Detail publikačního výsledku
The Thermodynamic Driving Force for Kinetics in General and Enzyme Kinetics in Particular
PEKAŘ, M.
Original Title
The Thermodynamic Driving Force for Kinetics in General and Enzyme Kinetics in Particular
English Title
The Thermodynamic Driving Force for Kinetics in General and Enzyme Kinetics in Particular
Type
WoS Article
Original Abstract
The thermodynamic driving force of a reaction is usually taken as the chemical potential difference between products and reactants. The forward and backward reaction rates are then related to this force. This procedure is of very limited validity, the resulting expression contains no kinetic factor and gives little information on reaction kinetics. The transformation of the reaction rate as a function of concentration (and temperature) into a function of chemical potential should be more properly performed as illustrated by a simple example of an enzymatic reaction. The proper thermodynamic driving force is the difference between the exponentials of the totaled chemical potentials of reactants and products.
English abstract
The thermodynamic driving force of a reaction is usually taken as the chemical potential difference between products and reactants. The forward and backward reaction rates are then related to this force. This procedure is of very limited validity, the resulting expression contains no kinetic factor and gives little information on reaction kinetics. The transformation of the reaction rate as a function of concentration (and temperature) into a function of chemical potential should be more properly performed as illustrated by a simple example of an enzymatic reaction. The proper thermodynamic driving force is the difference between the exponentials of the totaled chemical potentials of reactants and products.
Keywords
driving force, kinetics, reaction rate, thermodynamics
Key words in English
driving force, kinetics, reaction rate, thermodynamics
Authors
PEKAŘ, M.
RIV year
2016
Released
02.03.2015
ISBN
1439-4235
Periodical
CHEMPHYSCHEM
Volume
16
Number
4
State
Federal Republic of Germany
Pages from
884
Pages to
885
Pages count
2
Full text in the Digital Library
BibTex
@article{BUT113928,
author="Miloslav {Pekař}",
title="The Thermodynamic Driving Force for Kinetics in General and Enzyme Kinetics in Particular",
journal="CHEMPHYSCHEM",
year="2015",
volume="16",
number="4",
pages="884--885",
issn="1439-4235"
}