R&D result detail

Original Title

G4Hunter web application: a web server for G-quadruplex prediction

English Title

G4Hunter web application: a web server for G-quadruplex prediction

Type

WoS Article

Original Abstract

Motivation: Expanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community. Results: We developed a web version of the G4Hunter application. This new web-based server is a platform-independent and user-friendly application for quadruplex analyses. It allows retrieval of gene/nucleotide sequence entries from NCBI databases and provides complete characterization of localization and quadruplex propensity of quadruplex-forming sequences. The G4Hunter web application includes an interactive graphical data representation with many useful options including visualization, sorting, data storage and export. Availability and implementation: G4Hunter web application can be accessed at: http://bioinformat ics.ibp.cz.

English abstract

Motivation: Expanding research highlights the importance of guanine quadruplex structures. Therefore, easy-accessible tools for quadruplex analyses in DNA and RNA molecules are important for the scientific community. Results: We developed a web version of the G4Hunter application. This new web-based server is a platform-independent and user-friendly application for quadruplex analyses. It allows retrieval of gene/nucleotide sequence entries from NCBI databases and provides complete characterization of localization and quadruplex propensity of quadruplex-forming sequences. The G4Hunter web application includes an interactive graphical data representation with many useful options including visualization, sorting, data storage and export. Availability and implementation: G4Hunter web application can be accessed at: http://bioinformat ics.ibp.cz.

Keywords

G4Hunter, web server, G-quadruplex, prediction

Key words in English

G4Hunter, web server, G-quadruplex, prediction

Authors

BRÁZDA, V.; KOLOMAZNÍK, J.; LÝSEK, J.; BARTAS, M.; FOJTA, M.; ŠŤASTNÝ, J.; MERGNY, J.-L.

RIV year

2020

Released

05.02.2019

ISBN

1367-4803

Periodical

BIOINFORMATICS

Volume

35

Number

18

State

United Kingdom of Great Britain and Northern Ireland

Pages from

3493

Pages to

3495

Pages count

3

URL

https://doi.org/10.1093/bioinformatics/btz087

Full text in the Digital Library

http://hdl.handle.net/

BibTex

@article{BUT155984,
  author="BRÁZDA, V. and KOLOMAZNÍK, J. and LÝSEK, J. and BARTAS, M. and FOJTA, M. and ŠŤASTNÝ, J. and MERGNY, J.-L.",
  title="G4Hunter web application: a web server for G-quadruplex prediction",
  journal="BIOINFORMATICS",
  year="2019",
  volume="35",
  number="18",
  pages="3493--3495",
  doi="10.1093/bioinformatics/btz087",
  issn="1367-4803",
  url="https://doi.org/10.1093/bioinformatics/btz087"
}

Documents

bioinformatics_35_18_3493_s2
bioinformatics_35_18_3493