Project detail

Soluble materials for dried blood spot self-sampling and automated analysis

Duration: 01.02.2021 — 31.01.2022

Funding resources

Evropská unie - Interní grantová soutěž

- whole funder (2021-02-01 - 2022-01-31)

On the project

The project aims at the development of novel soluble materials for dried blood spot (DBS) self-sampling, their automated pretreatment and analysis. Simple DBS sampling, full solubility of the sampling materials and compatibility of sampling devices with commercial capillary electrophoresis will facilitate a fully autonomous process for biomedical assays. This will include DBS elution and clean-up, analyte extraction and quantitative analysis and will be exemplified by the determination of selected drugs as bio-medically relevant analytes.

Mark

FCH-K-21-7023

Default language

Czech

People responsible

Dorazilová Jana, Ing. - fellow researcher
Ryšavá Lenka, Ing., Ph.D. - principal person responsible

Units

Faculty of Chemistry
- (2021-02-01 - 2022-01-31)

Results

RYŠAVÁ, L.; DORAZILOVÁ, J.; DVOŘÁK, M.; VOJTOVÁ, L.; SEDLÁČEK, P.; KUBÁŇ, P. Development of soluble materials for dried blood spot sampling and analysis. Department of Analytical Chemistry, Faculty of Chemistry, Jagiellonian University in Krakow, Krakow 2021, 2021. p. 131-132.
Detail

KUBÁŇ, P.; RYŠAVÁ, L.; DVOŘÁK, M. Capillary electrophoresis for the automated extraction and analysis of dried blood spots in clinical analysis. 2021.
Detail

DORAZILOVÁ, J.; RYŠAVÁ, L.; SEDLÁČEK, P.; DVOŘÁK, M.; VOJTOVÁ, L.; KUBÁŇ, P. Vývoj 3D rozpustných polymerních sorbčních pěn specificky interagujících s krví pro klinické aplikace. Praha: České vysoké učení technické v Praze, 2021. s. 33-34.
Detail

RYŠAVÁ, L.; DVOŘÁK, M.; VOJTOVÁ, L.; DORAZILOVÁ, J.; SEDLÁČEK, P.; KUBÁŇ, P. Fully soluble polymeric foams for in-vial dried blood spot collection and analysis of acidic drugs by capillary electrophoresis. ANALYTICA CHIMICA ACTA, 2023, vol. 1241, no. 340793, ISSN: 0003-2670.
Detail

DVOŘÁK, M.; RYŠAVÁ, L.; MIRO, M.; KUBÁŇ, P. DIRECT ANALYSIS OF DRIED BLOOD SPOTS BY AUTOMATED SEQUENTIAL INJECTION-CAPILLARY ELECTROPHORESIS. 2021.
Detail

KUBÁŇ, P.; RYŠAVÁ, L.; DVOŘÁK, M. Capillary Electrophoresis for the Automated Extraction and Analysis of Dried Blood Spots in Clinical Analysis. 2021. p. 55-55.
Detail

BLANKA, M.; DVOŘÁK, M.; RYŠAVÁ, L.; GEBAUER, P.; MALÁ, Z.; KUBÁŇ, P. At-line coupling of hollow fiber liquid-phase microextraction to capillary electrophoresis for trace determination of acidic drugs in complex samples. Talanta, 2022, vol. 3, no. 2, p. 238-248. ISSN: 0039-9140.
Detail