Course detail

Biophysical Chemistry

FCH-MC_BFCHAcad. year: 2023/2024

The course focuses on the application of basic theoretical knowledge of physical chemistry to the biological systems. It represents a borderline course between physics, chemistry and biology, which allow obtaining molecular and structural perspective on biologically important and medically important pehnomena. Attention is drawn to an impact of the basic theoretical knowledge into analytical (advanced methods of study and interpretation of the structure and function of biopolymers) and application fields.

Guarantor

doc. Ing. Petr Sedláček, Ph.D.

Department

Institute of Physical and Applied Chemistry (ÚFSCH)

Learning outcomes of the course unit

Completing the course will result in knowledge on the essential principles of chemical thermodynamics and kinetics and their application to biological systems.

Prerequisites

Not applicable.

Co-requisites

Not applicable.

Recommended optional programme components

Not applicable.

Literature

Kodíček M. Karpenko V.: Biofysikální chemie. Academia, 2000 (CS)
Kalous V. Pavlíček Z.:Biofyzikální chemie. SNTL, 1980 (CS)
Atkins, P.: Physical chemistry for the life sciences. Oxford University Press ;W. H. Freeman and Company, 2006 (EN)
Cooper A. Biophysical Chemistry. Royal Society of Chemistry, 2011. Online version available at: (EN)

Planned learning activities and teaching methods

The course uses teaching methods in form of Lecture - 2 teaching hours per week. The e-learning system (LMS Moodle) is available to teachers and students.

Assesment methods and criteria linked to learning outcomes

Exam: written and oral

Language of instruction

Czech

Work placements

Not applicable.

Course curriculum

Syllabus divided to weekly given lectures:

1. Introduction to biophysical chemistry
2., 3. Role of molecular interactions
4., 5. Biological thermodynamics
6. Bioenergetics
7., 8. Phase transitions in biological systems
9. Binding equilibria
10. Function and properties of biological membranes
11. Non-equilibrium thermodynamics
12., 13. Biological kinetics

Aims

The main aim of the course is to apply the basic knowledge and theories of physical chemistry (both from the thermodynamic and kinetic point of view) on the living systems and phenomena.

Specification of controlled education, way of implementation and compensation for absences

Attendance to lectures is not required but is recommended.

Classification of course in study plans

  • Programme NKCP_CHCHTE Master's, 1. year of study, winter semester, 4 credits, compulsory
  • Programme NPCP_CHCHTE Master's, 1. year of study, winter semester, 4 credits, compulsory

  • Programme NPCP_CHMA Master's

    specialization CHBL , 1. year of study, winter semester, 4 credits, compulsory
    specialization BF , 1. year of study, winter semester, 4 credits, compulsory

  • Programme NPCP_CHPL Master's, 1. year of study, winter semester, 4 credits, compulsory
  • Programme NKCP_CHPL Master's, 1. year of study, winter semester, 4 credits, compulsory

Type of course unit

 

Lecture

26 hours, optionally

Teacher / Lecturer

doc. Ing. Petr Sedláček, Ph.D.

Guided consultation in combined form of studies

39 hours, optionally

Teacher / Lecturer

doc. Ing. Petr Sedláček, Ph.D.

Exercise

13 hours, compulsory

Teacher / Lecturer

doc. Ing. Petr Sedláček, Ph.D.