Course detail

Biochemistry I

FCH-BC_BCH1Acad. year: 2024/2025

Not applicable.

Language of instruction

Czech

Number of ECTS credits

4

Mode of study

Not applicable.

Entry knowledge

Not applicable.

Rules for evaluation and completion of the course

Not applicable.

Aims

Not applicable.

Study aids

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Alberts B. Bray G. a kol: Základy buněčné biologie. Espero Publishing, 2. vyd. (CS)
Vodrážka Z. : Biochemie. Academia, Praha 1996. (CS)

Recommended reading

Not applicable.

Classification of course in study plans

  • Programme BPCP_CHTPO Bachelor's

    specialization CHPL , 2 year of study, summer semester, compulsory
    specialization PCH , 2 year of study, summer semester, compulsory
    specialization BT , 2 year of study, summer semester, compulsory

  • Programme BKCP_CHTPO Bachelor's

    specialization PCH , 2 year of study, summer semester, compulsory
    specialization BT , 2 year of study, summer semester, compulsory
    specialization CHPL , 2 year of study, summer semester, compulsory

  • Programme BKCP_AAEFCH Bachelor's 2 year of study, summer semester, compulsory
  • Programme BKCP_CHCHTE Bachelor's 2 year of study, summer semester, compulsory
  • Programme BKCP_CHTM Bachelor's 2 year of study, summer semester, compulsory-optional
  • Programme BKCP_CHTOZP Bachelor's 2 year of study, summer semester, compulsory-optional
  • Programme BPCP_AAEFCH Bachelor's 2 year of study, summer semester, compulsory
  • Programme BPCP_CHCHTE Bachelor's 2 year of study, summer semester, compulsory
  • Programme BPCP_CHMA Bachelor's 2 year of study, summer semester, compulsory
  • Programme BPCP_CHTM Bachelor's 2 year of study, summer semester, compulsory-optional
  • Programme BPCP_CHTOZP Bachelor's 2 year of study, summer semester, compulsory-optional

  • Programme BPCP_CHTP Bachelor's

    specialization CHPL , 2 year of study, summer semester, compulsory
    specialization PCH , 2 year of study, summer semester, compulsory
    specialization BT , 2 year of study, summer semester, compulsory

  • Programme BKCP_CHTP Bachelor's

    specialization CHPL , 2 year of study, summer semester, compulsory
    specialization PCH , 2 year of study, summer semester, compulsory
    specialization BT , 2 year of study, summer semester, compulsory

  • Programme NPCP_CHTM Master's 1 year of study, summer semester, elective
    2 year of study, summer semester, elective
  • Programme NKCP_CHTM Master's 1 year of study, summer semester, elective
    2 year of study, summer semester, elective
  • Programme BPCP_MPMU Bachelor's 2 year of study, summer semester, compulsory

Type of course unit

 

Lecture

26 hod., optionally

Teacher / Lecturer

Syllabus

Osnova:

1. Látkové složení živé hmoty. Struktura buňky. Organizace biologických systémů.

2. Aminokyseliny. Peptidická vazba. Bílkoviny - struktura a stabilita, denaturace.

3. Metody izolace, purifikace a charakterizace biopolymerů .

4. Metody ke zjišťování struktury biomolekul a jejich změn.

5. Sacharidy - monosacharidy, oligosacharidy, polysacharidy, složené sacharidy.

6. Lipidy - struktura a klasifikace. Jednoduché a složené lipidy. Izoprenoidy. 

7. Biomembrány - struktura a funkce. Membránový transport.

8. Enzymy a biokatalýza. Substrátová specifita. Koenzymy. Regulace enzymové aktivity. Stručné názvosloví enzymů.

9. Enzymová kinetika. Rovnice Michaelise a Mentenové. Inhibice. Analýza kinetických dat. Reakce se dvěma substráty.

10. Bioenergetika, makroergické sloučeniny, metabolismus základních typů živin - centrální dráhy.

11. Metaboplismus sacharidů, lipidů, aminokyselin.

12. Biologické oxidace, - dýchací řetězec, fotosyntéza. Energetické spřažení. 

13. Nukleové kyseliny - typy, struktura DNA a RNA. Funkce v organismu, genetický kód. Replikace, transkripce, translace

Exercise

13 hod., compulsory

Teacher / Lecturer