Detail aplikovaného výsledku

Process for making fingolimod

Bohumil Dymacek, Reinerus Gerardus Gieling, Jozef Krajcovic

Originální název

Process for making fingolimod

Anglický název

Process for making fingolimod

Druh

Patent

Originální abstrakt

The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a solvent with hydrogen in a presence of a hydrogenation catalyst, preferably palladium catalyst, and optionally converting fingolimod of formula (1) into an acid addition salt, to compounds of formula (11) and (14), processes of making them and to their use in making fingolimod.

Anglický abstrakt

The invention relates to a process of making fingolimod of formula (1), or an acid addition salt thereof comprising a step of reacting the compound of formula (11) and/or a compound of formula (14) or an acid addition salt thereof, in a solvent with hydrogen in a presence of a hydrogenation catalyst, preferably palladium catalyst, and optionally converting fingolimod of formula (1) into an acid addition salt, to compounds of formula (11) and (14), processes of making them and to their use in making fingolimod.

Číslo patentu

WO2012041405A1

Datum přihlášky

22.12.2010

Datum zápisu

05.04.2012

Vlastník

SYNTHON B.V. Microweg 22 NL-6545 CM Nijmegen

Licenční poplatek

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