Detail publikačního výsledku
Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones
EL-SHAMY, I.; ABDEL-LATTIF, A.; FOUDA, M.; ALMONASY, N.; AL-DEYAB, S.; EL-HASHASH, M.
Originální název
Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones
Anglický název
Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones
Druh
Článek recenzovaný mimo WoS a Scopus
Originální abstrakt
The principal purpose of the present study is to synthesize and investigate the antimicrobial and antifungal activities of new 1, 3-selenazole derivatives having phthalazin-1(2H)-one moieties. A multi-step reaction route was developed to synthesize a several of targeted derivatives starting from 4-alkyl/aryl-phthalazin-1(2H)-one and 2-chloro-N-phenylacetamide. The structures of the synthesized compounds were confirmed by 1HNMR, 13CNMR, MS, IR spectroscopy and by elemental analysis. The antimicrobial and antifungal activities of all derivatives against four species of bacteria and two species of fungi were investigated. The antimicrobial and antifungal activity was determined in the extracts using disk diffusion method. Amoxicillin and Ketoconazole were used as standard drugs for the bacteria and fungi, respectively.
Anglický abstrakt
The principal purpose of the present study is to synthesize and investigate the antimicrobial and antifungal activities of new 1, 3-selenazole derivatives having phthalazin-1(2H)-one moieties. A multi-step reaction route was developed to synthesize a several of targeted derivatives starting from 4-alkyl/aryl-phthalazin-1(2H)-one and 2-chloro-N-phenylacetamide. The structures of the synthesized compounds were confirmed by 1HNMR, 13CNMR, MS, IR spectroscopy and by elemental analysis. The antimicrobial and antifungal activities of all derivatives against four species of bacteria and two species of fungi were investigated. The antimicrobial and antifungal activity was determined in the extracts using disk diffusion method. Amoxicillin and Ketoconazole were used as standard drugs for the bacteria and fungi, respectively.
Klíčová slova
Selenium, phthalazin-1(2H)-one, antimicrobial activity
Klíčová slova v angličtině
Selenium, phthalazin-1(2H)-one, antimicrobial activity
Autoři
EL-SHAMY, I.; ABDEL-LATTIF, A.; FOUDA, M.; ALMONASY, N.; AL-DEYAB, S.; EL-HASHASH, M.
Rok RIV
2014
Vydáno
18.10.2013
ISSN
1097-8135
Periodikum
Life Science Journal
Svazek
10
Číslo
4
Stát
Čínská lidová republika
Strany od
799
Strany do
809
Strany počet
11
Plný text v Digitální knihovně
BibTex
@article{BUT106135,
author="Ibrahim E. {El-Shamy} and Abdelmohsen Moustafa {Abdellatif} and Moustafa M.D. {Fouda} and Numan {Almonasy} and Salem S. {Al-Deyab} and Maher A. {El-Hashash}",
title="Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones",
journal="Life Science Journal",
year="2013",
volume="10",
number="4",
pages="799--809",
issn="1097-8135"
}