Detail publikačního výsledku

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

ČAPKA, L.; ZLÁMALOVÁ GARGOŠOVÁ, H.; VÁVROVÁ, M.

Originální název

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

Anglický název

Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs

Druh

Článek WoS

Originální abstrakt

This paper presents the use of UV-VIS spectrophotometry as a means of determining ecotoxicity. The method is based on spectrophotometric measuring of micro-algae Pseudokirchneriella subcapitata in water suspension. Six non-steroidal anti-inflammatory drugs (paracetamol, diclofenac, salicylic acid, ibuprofen, naproxen and ketoprofen) were selected as target compounds because they are the most commonly used human pharmaceuticals, which also means they are significant environmental pollutants. The 72hEC50 method was chosen for determination of ecotoxicity. The results reveal paracetamol (104 mg/L) and particularly ketoprofen (9 mg/L) as potentially ecotoxic compounds for aquatic organisms.

Anglický abstrakt

This paper presents the use of UV-VIS spectrophotometry as a means of determining ecotoxicity. The method is based on spectrophotometric measuring of micro-algae Pseudokirchneriella subcapitata in water suspension. Six non-steroidal anti-inflammatory drugs (paracetamol, diclofenac, salicylic acid, ibuprofen, naproxen and ketoprofen) were selected as target compounds because they are the most commonly used human pharmaceuticals, which also means they are significant environmental pollutants. The 72hEC50 method was chosen for determination of ecotoxicity. The results reveal paracetamol (104 mg/L) and particularly ketoprofen (9 mg/L) as potentially ecotoxic compounds for aquatic organisms.

Klíčová slova

Ecotoxicity, non-steroidal anti-inflammatory drugs, UV-VIS spectrophotometry

Klíčová slova v angličtině

Ecotoxicity, non-steroidal anti-inflammatory drugs, UV-VIS spectrophotometry

Autoři

ČAPKA, L.; ZLÁMALOVÁ GARGOŠOVÁ, H.; VÁVROVÁ, M.

Rok RIV

2016

Vydáno

01.12.2015

ISSN

1018-4619

Periodikum

Fresenius Environmental Bulletin

Svazek

24

Číslo

12

Stát

Spolková republika Německo

Strany od

4758

Strany do

4762

Strany počet

5

Plný text v Digitální knihovně

http://hdl.handle.net/

BibTex

@article{BUT119157,
  author="Lukáš {Alexa} and Helena {Zlámalová Gargošová} and Milada {Vávrová}",
  title="Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs",
  journal="Fresenius Environmental Bulletin",
  year="2015",
  volume="24",
  number="12",
  pages="4758--4762",
  issn="1018-4619"
}