Detail publikačního výsledku

Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization

ABDELLATIF, A.; ABDELRAHMAN, R.; KUBĚNA, I.; KOBĚRA, L.; SPOTZ, Z.; ZBONČÁK, M.; PŘIKRYL, R.; BRUS, J.; JANČÁŘ, J.

Originální název

Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization

Anglický název

Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization

Druh

Článek WoS

Originální abstrakt

Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first time by the freeze-dried process. Extraction process, morphology, mechanical properties, pore size, porosity, swelling ability, and degradation behavior of composites scaffold were investigated. CSGC hollow fibers were extracted from mycelium of Schizophyllum commune CSGC hollow fiber exhibited inner diameter of (600 ± 250 nm) and outer fiber diameter of (2.5 ± 0.5 µm). The results of swelling and hydrolytic degradation studies demonstrated that the physicochemical of CO/CSGC@AV was significantly enhanced by CSGC in a concentration-dependent manner. The mechanical property of the CO/CSGC@AV was improved after encapsulated AV into CSGC hollow fibers compared with native CO. The pore size and porosity of the CO/CSGC@AV were slightly decreased in the presence of AV. All these results suggested that the new dressing scaffold has a potential for clinical skin regeneration, particularly for infected chronic wounds and ulcers.

Anglický abstrakt

Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first time by the freeze-dried process. Extraction process, morphology, mechanical properties, pore size, porosity, swelling ability, and degradation behavior of composites scaffold were investigated. CSGC hollow fibers were extracted from mycelium of Schizophyllum commune CSGC hollow fiber exhibited inner diameter of (600 ± 250 nm) and outer fiber diameter of (2.5 ± 0.5 µm). The results of swelling and hydrolytic degradation studies demonstrated that the physicochemical of CO/CSGC@AV was significantly enhanced by CSGC in a concentration-dependent manner. The mechanical property of the CO/CSGC@AV was improved after encapsulated AV into CSGC hollow fibers compared with native CO. The pore size and porosity of the CO/CSGC@AV were slightly decreased in the presence of AV. All these results suggested that the new dressing scaffold has a potential for clinical skin regeneration, particularly for infected chronic wounds and ulcers.

Klíčová slova

Chitosan-glucan, hollow fiber, collagen, aloe vera, degradation, release properties

Klíčová slova v angličtině

Chitosan-glucan, hollow fiber, collagen, aloe vera, degradation, release properties

Autoři

ABDELLATIF, A.; ABDELRAHMAN, R.; KUBĚNA, I.; KOBĚRA, L.; SPOTZ, Z.; ZBONČÁK, M.; PŘIKRYL, R.; BRUS, J.; JANČÁŘ, J.

Rok RIV

2020

Vydáno

15.02.2020

ISSN

0144-8617

Periodikum

Carbohydrate Polymers

Svazek

5

Číslo

25

Stát

Spojené království Velké Británie a Severního Irska

Strany od

101

Strany do

117

Strany počet

15

URL

https://www.sciencedirect.com/science/article/pii/S0144861719313761

Plný text v Digitální knihovně

http://hdl.handle.net/

BibTex

@article{BUT160710,
  author="ABDELLATIF, A. and ABDELRAHMAN, R. and KUBĚNA, I. and KOBĚRA, L. and SPOTZ, Z. and ZBONČÁK, M. and PŘIKRYL, R. and BRUS, J. and JANČÁŘ, J.",
  title="Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization",
  journal="Carbohydrate Polymers",
  year="2020",
  volume="5",
  number="25",
  pages="101--117",
  doi="10.1016/j.carbpol.2019.115708",
  issn="0144-8617",
  url="https://www.sciencedirect.com/science/article/pii/S0144861719313761"
}