Detail publikačního výsledku

Skin protecting activity of microbial extracts

UHLÍŘOVÁ, R.; BOČÁN, D.; SKOUMALOVÁ, P.; MÁROVÁ, I.

Originální název

Skin protecting activity of microbial extracts

Anglický název

Skin protecting activity of microbial extracts

Druh

Abstrakt

Originální abstrakt

Microalgae and red yeast extracts contain a broad spectrum of compounds, which could serve as an alternative to conventional nutrient sour-ce. Moreover, the extracts contain antioxidants and can provide nutrition and protection of the skin.Presented work aims at preparation and characterization of liposome particles with complex aqueous and oil extracts of microbial origin. Active compounds as well as antioxidant activity and SPF were determined by HPLC and spectrophotometry. Most promising extracts were packed into liposome and PHB-liposome particles. Prepared particles were characterized by their encapsulation efficiency, particle size and poly-dispersity index together with colloidal stability. Antimicrobial activity was tested against S. epidermidis and E. coli. Prepared extracts and particles were evaluated by MTT assay on human keratinocytes HaCaT cell line whether they alter cell viability.Micro- and nanoparticles with encapsulated antioxidant and antimicrobial active compounds can enhance the effectiveness of cosmetics and pharmaceuticals. In this work, the potential use of liposome particles with natural microbial extracts in appropriate concentration was proposed. Liposomes regardless PHB enrichment are stable with desired properties and suitable for further application in cosmetics as well as in the food industry.

Anglický abstrakt

Microalgae and red yeast extracts contain a broad spectrum of compounds, which could serve as an alternative to conventional nutrient sour-ce. Moreover, the extracts contain antioxidants and can provide nutrition and protection of the skin.Presented work aims at preparation and characterization of liposome particles with complex aqueous and oil extracts of microbial origin. Active compounds as well as antioxidant activity and SPF were determined by HPLC and spectrophotometry. Most promising extracts were packed into liposome and PHB-liposome particles. Prepared particles were characterized by their encapsulation efficiency, particle size and poly-dispersity index together with colloidal stability. Antimicrobial activity was tested against S. epidermidis and E. coli. Prepared extracts and particles were evaluated by MTT assay on human keratinocytes HaCaT cell line whether they alter cell viability.Micro- and nanoparticles with encapsulated antioxidant and antimicrobial active compounds can enhance the effectiveness of cosmetics and pharmaceuticals. In this work, the potential use of liposome particles with natural microbial extracts in appropriate concentration was proposed. Liposomes regardless PHB enrichment are stable with desired properties and suitable for further application in cosmetics as well as in the food industry.

Klíčová slova

Microalgae, red yeast, antioxidant activity, antimicrobial activity, cytotoxicity, liposomes

Klíčová slova v angličtině

Microalgae, red yeast, antioxidant activity, antimicrobial activity, cytotoxicity, liposomes

Autoři

UHLÍŘOVÁ, R.; BOČÁN, D.; SKOUMALOVÁ, P.; MÁROVÁ, I.

Rok RIV

2022

Vydáno

01.12.2021

ISSN

2564-615X

Periodikum

The EuroBiotech Journal

Svazek

5

Číslo

s2

Stát

Italská republika

Strany od

84

Strany do

84

Strany počet

112

Plný text v Digitální knihovně

http://hdl.handle.net/

BibTex

@misc{BUT175344,
  author="Renata {Uhlířová} and David {Bočán} and Petra {Skoumalová} and Ivana {Márová}",
  title="Skin protecting activity of microbial extracts",
  year="2021",
  journal="The EuroBiotech Journal",
  volume="5",
  number="s2",
  pages="84--84",
  issn="2564-615X",
  note="Abstract"
}