Detail publikačního výsledku

Hybrid Enzymatic/Photocatalytic Degradation of Antibiotics via Morphologically Programmable Light-Driven ZnO Microrobots

ORAL, Ç.; USSIA, M.; PUMERA, M.

Originální název

Hybrid Enzymatic/Photocatalytic Degradation of Antibiotics via Morphologically Programmable Light-Driven ZnO Microrobots

Anglický název

Hybrid Enzymatic/Photocatalytic Degradation of Antibiotics via Morphologically Programmable Light-Driven ZnO Microrobots

Druh

Článek WoS

Originální abstrakt

Antibiotics are antimicrobial substances that can be used for preventive and therapeutic purposes in humans and animals. Their overdose usage has led to uncontrolled release to the environment, contributing significantly to the development of antimicrobial resistance phenomena. Here, enzyme-immobilized self-propelled zinc oxide (ZnO) microrobots are proposed to effectively target and degrade the released antibiotics in water bodies. Specifically, the morphology of the microrobots is tailored via the incorporation of Au during the synthetic process to lead the light-controlled motion into having on/off switching abilities. The microrobots are further modified with laccase enzyme by physical adsorption, and the immobilization process is confirmed by enzymatic activity measurements. Oxytetracycline (OTC) is used as a model of veterinary antibiotics to investigate the enzyme-immobilized microrobots for their removal capacities. The results demonstrate that the presence of laccase on the microrobot surfaces can enhance the removal of antibiotics via oxidation. This concept for immobilizing enzymes on self-propelled light-driven microrobots leads to the effective removal of the released antibiotics from water bodies with an environmentally friendly strategy.

Anglický abstrakt

Antibiotics are antimicrobial substances that can be used for preventive and therapeutic purposes in humans and animals. Their overdose usage has led to uncontrolled release to the environment, contributing significantly to the development of antimicrobial resistance phenomena. Here, enzyme-immobilized self-propelled zinc oxide (ZnO) microrobots are proposed to effectively target and degrade the released antibiotics in water bodies. Specifically, the morphology of the microrobots is tailored via the incorporation of Au during the synthetic process to lead the light-controlled motion into having on/off switching abilities. The microrobots are further modified with laccase enzyme by physical adsorption, and the immobilization process is confirmed by enzymatic activity measurements. Oxytetracycline (OTC) is used as a model of veterinary antibiotics to investigate the enzyme-immobilized microrobots for their removal capacities. The results demonstrate that the presence of laccase on the microrobot surfaces can enhance the removal of antibiotics via oxidation. This concept for immobilizing enzymes on self-propelled light-driven microrobots leads to the effective removal of the released antibiotics from water bodies with an environmentally friendly strategy.

Klíčová slova

laccase; micromotors; microswimmers; self-electrophoresis; water purification

Klíčová slova v angličtině

laccase; micromotors; microswimmers; self-electrophoresis; water purification

Autoři

ORAL, Ç.; USSIA, M.; PUMERA, M.

Rok RIV

2023

Vydáno

01.09.2022

Nakladatel

WILEY-V C H VERLAG GMBH

Místo

WEINHEIM

ISSN

1613-6829

Periodikum

Small

Svazek

18

Číslo

39

Stát

Spolková republika Německo

Strany od

2202600

Strany počet

8

URL

https://onlinelibrary.wiley.com/doi/10.1002/smll.202202600

BibTex

@article{BUT179165,
  author="Çaǧatay Mert {Oral} and Martina {Ussia} and Martin {Pumera}",
  title="Hybrid Enzymatic/Photocatalytic Degradation of Antibiotics via Morphologically Programmable Light-Driven ZnO Microrobots",
  journal="Small",
  year="2022",
  volume="18",
  number="39",
  pages="8",
  doi="10.1002/smll.202202600",
  issn="1613-6810",
  url="https://onlinelibrary.wiley.com/doi/10.1002/smll.202202600"
}