Detail publikačního výsledku

Fluorescence study of some structural and compositional effects on the aggregation of hydrophobized hyaluronan

VELCER, T.; MRAVEC, F.; VENEROVÁ, T.; CHANG, C.; PEKAŘ, M.

Originální název

Fluorescence study of some structural and compositional effects on the aggregation of hydrophobized hyaluronan

Anglický název

Fluorescence study of some structural and compositional effects on the aggregation of hydrophobized hyaluronan

Druh

Článek WoS

Originální abstrakt

The aggregation behavior of four samples of hydrophobically modified hyaluronan was examined in water and in 0.15 M NaCl. The samples differed in the length of their hydrocarbon modifying chains, degree of substitution, or hyaluronan molecular weight. The critical aggregation concentration was determined by fluorescence spec-troscopy using pyrene as a probe. Aggregation was observed even with hyaluronan modified by a short alkyl chain (C6). The critical aggregation concentration decreased with increasing alkyl chain length and with increasing hyaluronan molecular weight at a comparable degree of substitution. Aggregation was detected over a rather broad concentration interval, indicating a progressive formation of aggregates. Two populations of ag-gregates were detected for the oleyl substitution. The addition of NaCl had only minor effect on the critical aggregation concentration.

Anglický abstrakt

The aggregation behavior of four samples of hydrophobically modified hyaluronan was examined in water and in 0.15 M NaCl. The samples differed in the length of their hydrocarbon modifying chains, degree of substitution, or hyaluronan molecular weight. The critical aggregation concentration was determined by fluorescence spec-troscopy using pyrene as a probe. Aggregation was observed even with hyaluronan modified by a short alkyl chain (C6). The critical aggregation concentration decreased with increasing alkyl chain length and with increasing hyaluronan molecular weight at a comparable degree of substitution. Aggregation was detected over a rather broad concentration interval, indicating a progressive formation of aggregates. Two populations of ag-gregates were detected for the oleyl substitution. The addition of NaCl had only minor effect on the critical aggregation concentration.

Klíčová slova

Hydrophobically modified hyaluronan; Degree of substitution; Critical aggregation concentration; Fluorescence; Pyrene

Klíčová slova v angličtině

Hydrophobically modified hyaluronan; Degree of substitution; Critical aggregation concentration; Fluorescence; Pyrene

Autoři

VELCER, T.; MRAVEC, F.; VENEROVÁ, T.; CHANG, C.; PEKAŘ, M.

Rok RIV

2023

Vydáno

31.10.2022

Nakladatel

ELSEVIER

Místo

AMSTERDAM

ISSN

2215-0382

Periodikum

Colloid and Interface Science Communications

Svazek

51

Číslo

100667

Stát

Nizozemsko

Strany od

1

Strany do

6

Strany počet

6

URL

https://www.sciencedirect.com/science/article/pii/S2215038222000942?via%3Dihub

BibTex

@article{BUT181399,
  author="Tomáš {Velcer} and Filip {Mravec} and Tereza {Venerová} and Chien-Hsiang {Chang} and Miloslav {Pekař}",
  title="Fluorescence study of some structural and compositional effects on the aggregation of hydrophobized hyaluronan",
  journal="Colloid and Interface Science Communications",
  year="2022",
  volume="51",
  number="100667",
  pages="1--6",
  doi="10.1016/j.colcom.2022.100677",
  issn="2215-0382",
  url="https://www.sciencedirect.com/science/article/pii/S2215038222000942?via%3Dihub"
}