Detail publikačního výsledku

Gas-Free Amino- and Alkoxycarbonylation of Aryl Iodides in a Bioinspired Deep Eutectic Solvent with Mo(CO)6 as a Safe CO Source

MESSA, F.; PAPARELLA, A.; VESELÝ, D.; KRAJČOVIČ, J.; PAPADIA, P.; PERRONE, S.; SALOMONE, A.

Originální název

Gas-Free Amino- and Alkoxycarbonylation of Aryl Iodides in a Bioinspired Deep Eutectic Solvent with Mo(CO)6 as a Safe CO Source

Anglický název

Gas-Free Amino- and Alkoxycarbonylation of Aryl Iodides in a Bioinspired Deep Eutectic Solvent with Mo(CO)6 as a Safe CO Source

Druh

Článek WoS

Originální abstrakt

The Pd-catalyzed amino- and alkoxycarbonylation of aryl iodides has been exploited, for the first time, in a bioinspired Deep Eutectic Solvent and under gas-free conditions, by using Mo(CO)(6) as the CO source. The method allows for the preparation of carboxylic amides and esters in high yields (up to 99 %), short reaction time (2 h) and under mild reaction conditions (80 degrees C), with a low catalyst loading (2.5 mol %). Noteworthy, in the case of N-hexylbenzamide, it has been demonstrated that both the catalyst and DES can be used for four consecutive runs, with a moderate decrease of catalytic efficiency. The methodology has been also applied to the preparation of an Active Pharmaceutical Ingredient used for the treatment of human scabies and lice.

Anglický abstrakt

The Pd-catalyzed amino- and alkoxycarbonylation of aryl iodides has been exploited, for the first time, in a bioinspired Deep Eutectic Solvent and under gas-free conditions, by using Mo(CO)(6) as the CO source. The method allows for the preparation of carboxylic amides and esters in high yields (up to 99 %), short reaction time (2 h) and under mild reaction conditions (80 degrees C), with a low catalyst loading (2.5 mol %). Noteworthy, in the case of N-hexylbenzamide, it has been demonstrated that both the catalyst and DES can be used for four consecutive runs, with a moderate decrease of catalytic efficiency. The methodology has been also applied to the preparation of an Active Pharmaceutical Ingredient used for the treatment of human scabies and lice.

Klíčová slova

alkoxycarbonylation; aminocarbonylation; Pd-catalysis; deep eutectic solvent; molybdenum hexacarbonyl

Klíčová slova v angličtině

alkoxycarbonylation; aminocarbonylation; Pd-catalysis; deep eutectic solvent; molybdenum hexacarbonyl

Autoři

MESSA, F.; PAPARELLA, A.; VESELÝ, D.; KRAJČOVIČ, J.; PAPADIA, P.; PERRONE, S.; SALOMONE, A.

Rok RIV

2024

Vydáno

22.05.2023

Nakladatel

Wiley-VCH

Místo

WEINHEIM

ISSN

1434-193X

Periodikum

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Svazek

26

Číslo

24

Stát

Spolková republika Německo

Strany od

1

Strany do

8

Strany počet

8

URL

https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ejoc.202300309

Plný text v Digitální knihovně

http://hdl.handle.net/11012/244939

BibTex

@article{BUT184175,
  author="Francesco {Messa} and Andrea Nicola {Paparella} and Dominik {Veselý} and Jozef {Krajčovič} and Paride {Papadia} and Serena {Perrone} and Antonio {Salomone}",
  title="Gas-Free Amino- and Alkoxycarbonylation of Aryl Iodides in a Bioinspired Deep Eutectic Solvent with Mo(CO)6 as a Safe CO Source",
  journal="EUROPEAN JOURNAL OF ORGANIC CHEMISTRY",
  year="2023",
  volume="26",
  number="24",
  pages="1--8",
  doi="10.1002/ejoc.202300309",
  issn="1434-193X",
  url="https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ejoc.202300309"
}

Dokumenty

2023-Messa