Detail publikačního výsledku
Interaction of drugs with soil organic matter studied by microcalorimetry
KROUSKÁ, J.; PAPKO, N.; KLUČÁKOVÁ, M.
Originální název
Interaction of drugs with soil organic matter studied by microcalorimetry
Anglický název
Interaction of drugs with soil organic matter studied by microcalorimetry
Druh
Stať ve sborníku v databázi WoS či Scopus
Originální abstrakt
The usage of pharmaceuticals increases worldwide every year. The residues of these substances are excreted by the human or animal bodies and thus come into direct contact with the environment, mainly soils and ground water. The accumulation of pharmaceuticals in natural ecosystems may be problematic in the future therefore the knowledge of their behaviour, transport and interactions in the ecosystems is essential for their treatment. The most reactive substances in soils are humic as well as fulvic substances. Two fulvic acids stand as the model reactants with different pharmaceuticals in this study. These reactive compounds contain several kinds of active functional groups, such as hydrophilic hydroxylic or carboxylic groups, and also diverse hydrophobic structures. The interactions between fulvic acids and solutions of pure drugs were studied by isothermal titration calorimetry. The aim of the study was to observe the heat effects of the interactions and to describe the intensity of the binding process.
Anglický abstrakt
The usage of pharmaceuticals increases worldwide every year. The residues of these substances are excreted by the human or animal bodies and thus come into direct contact with the environment, mainly soils and ground water. The accumulation of pharmaceuticals in natural ecosystems may be problematic in the future therefore the knowledge of their behaviour, transport and interactions in the ecosystems is essential for their treatment. The most reactive substances in soils are humic as well as fulvic substances. Two fulvic acids stand as the model reactants with different pharmaceuticals in this study. These reactive compounds contain several kinds of active functional groups, such as hydrophilic hydroxylic or carboxylic groups, and also diverse hydrophobic structures. The interactions between fulvic acids and solutions of pure drugs were studied by isothermal titration calorimetry. The aim of the study was to observe the heat effects of the interactions and to describe the intensity of the binding process.
Klíčová slova
Humic substances, drug, interaction, microcalorimetry
Klíčová slova v angličtině
Humic substances, drug, interaction, microcalorimetry
Autoři
KROUSKÁ, J.; PAPKO, N.; KLUČÁKOVÁ, M.
Rok RIV
2024
Vydáno
23.11.2022
Místo
Brno
ISBN
978-80-88365-09-9
Kniha
Proceedings 14th International Conference on Nanomaterials - Research & Application
Strany od
255
Strany do
259
Strany počet
5
Plný text v Digitální knihovně
BibTex
@inproceedings{BUT187703,
author="Jitka {Krouská} and Nadezhda {Papko} and Martina {Klučáková}",
title="Interaction of drugs with soil organic matter studied by microcalorimetry",
booktitle="Proceedings 14th International Conference on Nanomaterials - Research & Application",
year="2022",
pages="255--259",
address="Brno",
doi="10.37904/nanocon.2022.4615",
isbn="978-80-88365-09-9"
}