Detail publikačního výsledku

Interaction of drugs with soil organic matter studied by microcalorimetry

KROUSKÁ, J.; PAPKO, N.; KLUČÁKOVÁ, M.

Originální název

Interaction of drugs with soil organic matter studied by microcalorimetry

Anglický název

Interaction of drugs with soil organic matter studied by microcalorimetry

Druh

Stať ve sborníku v databázi WoS či Scopus

Originální abstrakt

The usage of pharmaceuticals increases worldwide every year. The residues of these substances are excreted by the human or animal bodies and thus come into direct contact with the environment, mainly soils and ground water. The accumulation of pharmaceuticals in natural ecosystems may be problematic in the future therefore the knowledge of their behaviour, transport and interactions in the ecosystems is essential for their treatment. The most reactive substances in soils are humic as well as fulvic substances. Two fulvic acids stand as the model reactants with different pharmaceuticals in this study. These reactive compounds contain several kinds of active functional groups, such as hydrophilic hydroxylic or carboxylic groups, and also diverse hydrophobic structures. The interactions between fulvic acids and solutions of pure drugs were studied by isothermal titration calorimetry. The aim of the study was to observe the heat effects of the interactions and to describe the intensity of the binding process.

Anglický abstrakt

The usage of pharmaceuticals increases worldwide every year. The residues of these substances are excreted by the human or animal bodies and thus come into direct contact with the environment, mainly soils and ground water. The accumulation of pharmaceuticals in natural ecosystems may be problematic in the future therefore the knowledge of their behaviour, transport and interactions in the ecosystems is essential for their treatment. The most reactive substances in soils are humic as well as fulvic substances. Two fulvic acids stand as the model reactants with different pharmaceuticals in this study. These reactive compounds contain several kinds of active functional groups, such as hydrophilic hydroxylic or carboxylic groups, and also diverse hydrophobic structures. The interactions between fulvic acids and solutions of pure drugs were studied by isothermal titration calorimetry. The aim of the study was to observe the heat effects of the interactions and to describe the intensity of the binding process.

Klíčová slova

Humic substances, drug, interaction, microcalorimetry

Klíčová slova v angličtině

Humic substances, drug, interaction, microcalorimetry

Autoři

KROUSKÁ, J.; PAPKO, N.; KLUČÁKOVÁ, M.

Rok RIV

2024

Vydáno

23.11.2022

Místo

Brno

ISBN

978-80-88365-09-9

Kniha

Proceedings 14th International Conference on Nanomaterials - Research & Application

Strany od

255

Strany do

259

Strany počet

5

Plný text v Digitální knihovně

BibTex

@inproceedings{BUT187703,
  author="Jitka {Krouská} and Nadezhda {Papko} and Martina {Klučáková}",
  title="Interaction of drugs with soil organic matter studied by microcalorimetry",
  booktitle="Proceedings 14th International Conference on Nanomaterials - Research & Application",
  year="2022",
  pages="255--259",
  address="Brno",
  doi="10.37904/nanocon.2022.4615",
  isbn="978-80-88365-09-9"
}