Detail publikačního výsledku

Development of LC-MS method enabling full chromatographic separation of 36 pyrrolizidine alkaloids in plant-based matrices

WAWROSZOVÁ, S.; ČUMOVÁ, M.; ŠTĚPÁN, R.; PLUHÁČKOVÁ, H.; KOMENDOVÁ; R.

Originální název

Anglický název

Development of LC-MS method enabling full chromatographic separation of 36 pyrrolizidine alkaloids in plant-based matrices

Druh

Článek WoS

Originální abstrakt

Highlights • A comprehensive LC–MS/MS method was developed for simultaneous detection of 36 PAs. • Complete separation of isomeric PAs, including Senecionine and Intermedine groups. • Optimized QuPPe (Quick Polar Pesticides) extraction enabled rapid, simple, and cost-effective sample preparation. • Method validated across multiple plant-based matrices with LOQs from 2 to 10 μg/kg.

Anglický abstrakt

Klíčová slova

Pyrrolizidine alkaloids, Isomers, Liquid chromatography tandem mass spectrometry, Method development, Food safety

Klíčová slova v angličtině

Pyrrolizidine alkaloids, Isomers, Liquid chromatography tandem mass spectrometry, Method development, Food safety

Autoři

WAWROSZOVÁ, S.; ČUMOVÁ, M.; ŠTĚPÁN, R.; PLUHÁČKOVÁ, H.; KOMENDOVÁ; R.

Vydáno

29.08.2025

Periodikum

Analytica Chimica Acta

Svazek

1375

Číslo

Stát

Nizozemsko

Strany od

Strany do

Strany počet

URL

https://doi.org/10.1016/j.aca.2025.344577

BibTex

@article{BUT198611,
  author="WAWROSZOVÁ, S. and ČUMOVÁ, M. and ŠTĚPÁN, R. and PLUHÁČKOVÁ, H. and KOMENDOVÁ and R.",
  title="Development of LC-MS method enabling full chromatographic separation of 36 pyrrolizidine alkaloids in plant-based matrices",
  journal="Analytica Chimica Acta",
  year="2025",
  volume="1375",
  number="15",
  pages="1--12",
  doi="10.1016/j.aca.2025.344577",
  issn="0003-2670",
  url="https://doi.org/10.1016/j.aca.2025.344577"
}