Detail publikačního výsledku

Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles

MRAVEC, F.; CHIU, C.; CHANG, C.

Originální název

Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles

Anglický název

Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles

Druh

Kapitola, resp. kapitoly v odborné knize

Originální abstrakt

Ion pair amphiphile, prepared from mixed cationic/anionic surfactants, has a pseudodouble-chain structure and can be used as a raw material to form a vesicular structure, or catanionic vesicle, in aqueous phase. It has been demonstrated that catanionic vesicles could be fabricated from the ion pair amphiphile hexadecyltrimethylammonium-dodecylsulfate (HTMA:DS) by using a forced formation process with the addition of double-chain cationic surfactants, dialkyldimethylammonium bromide (DXDAB), and the physical stability of the HTMA:DS/DXDAB catanionic vesicles could be further improved in the presence of cholesterol. Through the analysis of bilayer fluidity and solvation, as well as the data integration of different analysis methods, combined with molecular dynamics simulations, the complex effects of the added cholesterol on the molecular arrangement and interaction in the bilayer structures of the HTMA:DS/DXDAB catanionic vesicles were elucidated.

Anglický abstrakt

Ion pair amphiphile, prepared from mixed cationic/anionic surfactants, has a pseudodouble-chain structure and can be used as a raw material to form a vesicular structure, or catanionic vesicle, in aqueous phase. It has been demonstrated that catanionic vesicles could be fabricated from the ion pair amphiphile hexadecyltrimethylammonium-dodecylsulfate (HTMA:DS) by using a forced formation process with the addition of double-chain cationic surfactants, dialkyldimethylammonium bromide (DXDAB), and the physical stability of the HTMA:DS/DXDAB catanionic vesicles could be further improved in the presence of cholesterol. Through the analysis of bilayer fluidity and solvation, as well as the data integration of different analysis methods, combined with molecular dynamics simulations, the complex effects of the added cholesterol on the molecular arrangement and interaction in the bilayer structures of the HTMA:DS/DXDAB catanionic vesicles were elucidated.

Klíčová slova

Bilayer fluidity; Catanionic bilayer; Catanionic vesicle; Ion pair amphiphile; Vesicular structure

Klíčová slova v angličtině

Bilayer fluidity; Catanionic bilayer; Catanionic vesicle; Ion pair amphiphile; Vesicular structure

Autoři

MRAVEC, F.; CHIU, C.; CHANG, C.

Vydáno

07.10.2025

Nakladatel

Springer Nature Singapore

Místo

Singapore

ISBN

9789819667277

Kniha

Physical Chemistry in Action, Colloids and Interfacial Dynamics

Strany od

247

Strany do

266

Strany počet

20

BibTex

@inbook{BUT199015,
  author="{} and Filip {Mravec} and  {} and  {} and  {} and Chien-Hsiang {Chang} and  {} and  {} and  {}",
  title="Roles of Cholesterol in Controlling Characteristics of Catanionic Vesicles",
  booktitle="Physical Chemistry in Action, Colloids and Interfacial Dynamics",
  year="2025",
  publisher="Springer Nature Singapore",
  address="Singapore",
  pages="247--266",
  isbn="9789819667277"
}