Detail publikačního výsledku

Hyaluronan-Arginine Interactions-An Ultrasound and ITC Study

JUGL, A.; PEKAŘ, M.

Originální název

Hyaluronan-Arginine Interactions-An Ultrasound and ITC Study

Anglický název

Hyaluronan-Arginine Interactions-An Ultrasound and ITC Study

Druh

Článek WoS

Originální abstrakt

High-resolution ultrasound spectroscopy and isothermal titration calorimetry were used to characterize interactions between hyaluronan and arginine oligomers. The molecular weight of arginine oligomer plays an important role in interactions with hyaluronan. Interactions were observable for arginine oligomers with eight monomer units and longer chains. The effect of the ionic strength and molecular weight of hyaluronan on interactions was tested. In an environment with increased ionic strength, the length of the arginine oligomer was crucial. Generally, sufficiently high ionic strength suppresses interactions between hyaluronan and arginine oligomers, which demonstrated interactions in water. From the point of view of the molecular weight of hyaluronan, the transition between the rod conformation and the random coil conformation appeared to be important.

Anglický abstrakt

High-resolution ultrasound spectroscopy and isothermal titration calorimetry were used to characterize interactions between hyaluronan and arginine oligomers. The molecular weight of arginine oligomer plays an important role in interactions with hyaluronan. Interactions were observable for arginine oligomers with eight monomer units and longer chains. The effect of the ionic strength and molecular weight of hyaluronan on interactions was tested. In an environment with increased ionic strength, the length of the arginine oligomer was crucial. Generally, sufficiently high ionic strength suppresses interactions between hyaluronan and arginine oligomers, which demonstrated interactions in water. From the point of view of the molecular weight of hyaluronan, the transition between the rod conformation and the random coil conformation appeared to be important.

Klíčová slova

hyaluronan; arginine; interaction; high-resolution ultrasound spectroscopy; isothermal titration calorimetry

Klíčová slova v angličtině

hyaluronan; arginine; interaction; high-resolution ultrasound spectroscopy; isothermal titration calorimetry

Autoři

JUGL, A.; PEKAŘ, M.

Rok RIV

2021

Vydáno

12.09.2020

Nakladatel

MDPI

Místo

BASEL

ISSN

2073-4360

Periodikum

Polymers

Svazek

12

Číslo

9

Stát

Švýcarská konfederace

Strany od

1

Strany do

20

Strany počet

20

URL

https://www.mdpi.com/2073-4360/12/9/2069

Plný text v Digitální knihovně

http://hdl.handle.net/11012/195577

BibTex

@article{BUT165162,
  author="Adam {Jugl} and Miloslav {Pekař}",
  title="Hyaluronan-Arginine Interactions-An Ultrasound and ITC Study",
  journal="Polymers",
  year="2020",
  volume="12",
  number="9",
  pages="1--20",
  doi="10.3390/polym12092069",
  issn="2073-4360",
  url="https://www.mdpi.com/2073-4360/12/9/2069"
}

Dokumenty

polymers-12-02069