Detail projektu
Design and analysis of novel extracellular matrix mimicking materials with tailored internal architecture targeted for drug delivery systems
Období řešení: 01.02.2021 — 31.01.2022
Zdroje financování
Evropská unie - Interní grantová soutěž
- plně financující (2021-02-01 - 2022-01-31)
O projektu
Proposed project focuses on design of biopolymer network with internal structure modified by self-assembly of phospholipid (lecithin) with the potential use as novel extracellular matrix (ECM) model in drug delivery systems. This project takes aim to precisely characterize application-relevant properties (structural for xerogels, transport and mechanical for hydrogels) and their mutual interconnections to evaluate potential usage of these novel materials in biomedical application.
Označení
FCH-K-21-7056
Originální jazyk
čeština
Řešitelé
Heger Richard, Ing. - hlavní řešitel
Kadlec Martin, Ing. - spoluřešitel
Trudičová Monika, Ing. - spoluřešitel
Zinkovska Natalia, Ing. - spoluřešitel
Útvary
Fakulta chemická
- příjemce (01.02.2021 - 31.01.2022)
Výsledky
HEGER, R.; KADLEC, M.; ZINKOVSKA, N.; TRUDIČOVÁ, M.; SMILEK, J. Lecithin as internal architecture modifier of hydrogels for model drug delivery systems with tunable properties. 35th Conference of the European Colloid & Interface Society, Book of Abstracts (Poster Presentations). 2021. p. 255-255.
Detail
HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; ZINKOVSKA, N.; HAJZLER, J.; PEKAŘ, M.; SMILEK, J. Novel Hydrogel Material with Tailored Internal Architecture Modified by “Bio” Amphiphilic Components—Design and Analysis by a Physico-Chemical Approach. Gels, 2022, vol. 8, no. 2, p. 1-23. ISSN: 2310-2861.
Detail
ZINKOVSKA, N.; HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; SMILEK, J. How the presence of lecithin nanodomains affects the transport properties of hydrogels - potential controlled release drug delivery. Nanocon 2021 - Abstracts. Ostrava, CZ: Tanger Ltd., 2021. p. 95-95. ISBN: 978-80-88365-00-6.
Detail
HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; ZINKOVSKA, N.; SMILEK, J. Structural and Mechanical Analyses of Hydrogel Systems Modified by Lecithin Nanodomains. Nanocon 2021 - Abstracts. Ostrava, CZ: Tanger Ltd., 2021. p. 96-96. ISBN: 978-80-88365-00-6.
Detail