Detail projektu

Design and analysis of novel extracellular matrix mimicking materials with tailored internal architecture targeted for drug delivery systems

Období řešení: 01.02.2021 — 31.01.2022

O projektu

Proposed project focuses on design of biopolymer network with internal structure modified by self-assembly of phospholipid (lecithin) with the potential use as novel extracellular matrix (ECM) model in drug delivery systems. This project takes aim to precisely characterize application-relevant properties (structural for xerogels, transport and mechanical for hydrogels) and their mutual interconnections to evaluate potential usage of these novel materials in biomedical application.

Označení

FCH-K-21-7056

Originální jazyk

čeština

Řešitelé

Heger Richard, Ing. - hlavní řešitel
Kadlec Martin, Ing. - spoluřešitel
Trudičová Monika, Ing. - spoluřešitel
Zinkovska Natalia, Ing. - spoluřešitel

Útvary

Fakulta chemická
- příjemce (01.02.2021 - 31.01.2022)

Zdroje financování

Evropská unie - Interní grantová soutěž

- plně financující (2021-02-01 - 2022-01-31)

Výsledky

HEGER, R.; KADLEC, M.; ZINKOVSKA, N.; TRUDIČOVÁ, M.; SMILEK, J. Lecithin as internal architecture modifier of hydrogels for model drug delivery systems with tunable properties. 35th Conference of the European Colloid & Interface Society, Book of Abstracts (Poster Presentations). 2021. p. 255-255.
Detail

ZINKOVSKA, N.; HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; SMILEK, J. How the presence of lecithin nanodomains affects the transport properties of hydrogels - potential controlled release drug delivery. Nanocon 2021 - Abstracts. Ostrava, CZ: Tanger Ltd., 2021. p. 95-95. ISBN: 978-80-88365-00-6.
Detail

HEGER, R.; KADLEC, M.; TRUDIČOVÁ, M.; ZINKOVSKA, N.; SMILEK, J. Structural and Mechanical Analyses of Hydrogel Systems Modified by Lecithin Nanodomains. Nanocon 2021 - Abstracts. Ostrava, CZ: Tanger Ltd., 2021. p. 96-96. ISBN: 978-80-88365-00-6.
Detail