Detail publikace

Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli

KOLÁŘ, R. VIČAR, T. CHMELÍK, J. JAKUBÍČEK, R. ODSTRČILÍK, J. NOHEL, M. SKORKOVSKÁ, K. TORNOW, R.

Originální název

Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

This paper describes a compact video-ophthalmoscope (VO) designed for capturing retinal video sequences of the optic nerve head (ONH) under flicker light stimulation. The device uses an OLED display and a fiber optic-coupled LED light source, enabling high-frame-rate video at low illumination intensity (12 mu W/cm2). Retinal responses were recorded in 10 healthy subjects during flicker light exposure with a pupil irradiance of 2 mu W/cm2. Following 20 s of stimulation, all subjects displayed changes in retinal reflectance and pulsation attenuation, linked to blood flow and volume variations. These findings suggest that increased blood volume leads to decreased retinal reflectance. Temporal analysis confirmed the ability to capture flicker-induced retinal reflectance changes, indicating its potential for spatial and temporal analysis. Overall, this device offers a portable approach for investigating dynamic retinal responses to light stimuli, which can aid the diagnosis of retinal diseases like diabetic retinopathy, glaucoma, or neurodegenerative diseases affecting retinal blood circulation.

Klíčová slova

blood volume; fundus reflectance; light flickering; neurovascular coupling; optic nerve head; video-ophthalmoscopy

Autoři

KOLÁŘ, R.; VIČAR, T.; CHMELÍK, J.; JAKUBÍČEK, R.; ODSTRČILÍK, J.; NOHEL, M.; SKORKOVSKÁ, K.; TORNOW, R.

Vydáno

11. 3. 2025

Nakladatel

WILEY-V C H VERLAG GMBH

Místo

WEINHEIM

ISSN

1864-0648

Periodikum

Journal of Biophotonics

Ročník

2025

Číslo

3

Stát

Spolková republika Německo

Strany počet

10

URL

https://onlinelibrary.wiley.com/doi/10.1002/jbio.202400494

BibTex

@article{BUT197697,
  author="Radim {Kolář} and Tomáš {Vičar} and Jiří {Chmelík} and Roman {Jakubíček} and Jan {Odstrčilík} and Michal {Nohel} and Karolína {Skorkovská} and Ralf-Peter {Tornow}",
  title="Compact Monocular Video-Ophthalmoscope to Measure Retinal Reflectance Changes to Flicker Light Stimuli",
  journal="Journal of Biophotonics",
  year="2025",
  volume="2025",
  number="3",
  pages="10",
  doi="10.1002/jbio.202400494",
  issn="1864-0648",
  url="https://onlinelibrary.wiley.com/doi/10.1002/jbio.202400494"
}