Detail publikace

Upcycling atmospheric CO2 to polyhydroxyalkanoates via sequential chemo-biocatalytic processes

By Bruch, M. Sanchez-Velandia, JE. Rodriguez-Pereira, J. Rich, M. Pearcy, N. Narancic, T. Garcia-Verdugo, E. Sans, V. O'Connor, K. Zanatta, M

Originální název

Upcycling atmospheric CO2 to polyhydroxyalkanoates via sequential chemo-biocatalytic processes

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The reduction of greenhouse gas emissions and the shift away from petrochemical-derived materials are critical goals in modern industrial development and societal progress. Addressing these intertwined challenges demands innovative and sustainable solutions. Here, we present the first example of synthesizing poly[R-(-)-3-hydroxybutyrate] (PHB) from atmospheric CO2, utilizing a streamlined and integrated process that combines both chemo- and bio-catalytic conditions. Central to our approach is the development of an immobilized catalytic system that efficiently converts atmospheric CO2 into sodium formate, establishing a sustainable carbon source for formatotrophic organisms. Through Adaptive Laboratory Evolution (ALE), we enhanced the growth rate of the bacterium Cupriavidus necator H16, enabling it to utilize formic acid and formate as the sole carbon and energy sources. The evolved strain, C. necator ALE26, achieved a 1.8-fold increase in the maximum growth rate (mu(max) = 0.25 +/- 0.02 h(-1)), attributed to the loss of the megaplasmid pHG1. Employing the adapted strain, we report the highest PHB production rate in continuous fermentation using C. necator for growth on formate. The development of the different stages (sorption and chemo- and bio-transformation) under compatible conditions that minimize the number of work-up stages demonstrates a major advancement in converting atmospheric CO2 into valuable biopolymers, thus simultaneously contributing to the reduction of greenhouse gases in the atmosphere and to a circular economy of biobased polymers that diminish fossil fuel dependence.

Klíčová slova

FORMIC-ACID, RALSTONIA-EUTROPHA, CARBON-DIOXIDE

Autoři

By Bruch, M.; Sanchez-Velandia, JE.; Rodriguez-Pereira, J.; Rich, M.; Pearcy, N.; Narancic, T.; Garcia-Verdugo, E.; Sans, V.; O'Connor, K.; Zanatta, M

Vydáno

9. 12. 2024

Nakladatel

ROYAL SOC CHEMISTRY

Místo

CAMBRIDGE

ISSN

1463-9262

Periodikum

GREEN CHEMISTRY

Ročník

26

Číslo

24

Stát

Spojené království Velké Británie a Severního Irska

Strany od

11885

Strany do

1189

Strany počet

14

URL

BibTex

@article{BUT191210,
  author="Jhonatan {Rodriguez Pereira} and Manuel {Bruch} and Julian E. {Sanchez-Velandia, Julian E.} and Michelle {Rich} and Nicole {Pearcy} and Tanja {Narančić} and Eduardo {Garcia-Verdugo} and Víctor {Sans} and Kevin {O'Connor} and Marcileia {Zanatta}",
  title="Upcycling atmospheric CO2 to polyhydroxyalkanoates via sequential chemo-biocatalytic processes",
  journal="GREEN CHEMISTRY",
  year="2024",
  volume="26",
  number="24",
  pages="11885--1189",
  doi="10.1039/d4gc04228j",
  issn="1463-9262",
  url="https://pubs.rsc.org/en/content/articlelanding/2024/gc/d4gc04228j"
}